Findings

What do systematic reviews say?

1,156 questions · 1,179 findings · 198 reviews · Headline outcomes only

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No studies found 250 · 21.2%GRADE not reported 43 · 3.6%Very low 236 · 20%Low 395 · 33.5%Moderate 208 · 17.6%High 47 · 4%

Herbal preparations vs medication

Fibroid volume (cm³) · women with uterine fibroids

1 finding from 1 review

Herbal preparations for uterine fibroids 2013 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Herbal preparations vs medication

Uterine size (cm3) ‐ · women with uterine fibroids

1 finding from 1 review

Herbal preparations for uterine fibroids 2013 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Acupuncture vs medication

Pain up to 1 month after treatment VAS2 · patients with fibromyalgia

1 finding from 1 review

Acupuncture for treating fibromyalgia 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 38 participants
Low

Acupuncture vs medication

Physical function · patients with fibromyalgia

The review found no eligible studies for this question.

1 finding from 1 review

Acupuncture for treating fibromyalgia 2013 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Acupuncture vs medication

Global well‐being: rated by participants · patients with fibromyalgia

The review found no eligible studies for this question.

1 finding from 1 review

Acupuncture for treating fibromyalgia 2013 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Acupuncture vs medication

Sleep · patients with fibromyalgia

The review found no eligible studies for this question.

1 finding from 1 review

Acupuncture for treating fibromyalgia 2013 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Acupuncture vs medication

Fatigue · patients with fibromyalgia

The review found no eligible studies for this question.

1 finding from 1 review

Acupuncture for treating fibromyalgia 2013 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Acupuncture vs medication

Stiffness · patients with fibromyalgia

The review found no eligible studies for this question.

1 finding from 1 review

Acupuncture for treating fibromyalgia 2013 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Acupuncture vs medication

Adverse events · patients with fibromyalgia

1 finding from 1 review

Acupuncture for treating fibromyalgia 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 38 participants
Low

Second generation antidepressant vs placebo medication

Depressive disorder according to DSM or ICD criteriaClinician diagnostic interview · patients with depressive disorders in children and adolescents

1 finding from 1 review

Newer generation antidepressants for depressive disorders in children and adolescents 2012 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Second generation antidepressant vs placebo medication

Suicide completionCompleted suicide rates · patients with depressive disorders in children and adolescents

1 finding from 1 review

Newer generation antidepressants for depressive disorders in children and adolescents 2012 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Second generation antidepressant vs placebo medication

Remission or response (as defined in trial) · patients with depressive disorders in children and adolescents

Second generation antidepressant probably leads to higher remission or response (as defined in trial) compared with placebo (by medication) (moderate certainty).

1 finding from 1 review

Newer generation antidepressants for depressive disorders in children and adolescents 2012 · Cochrane Headline outcomes only
RR 1.18 [1.08, 1.28]
16 studies · 2924 participants
Moderate

Second generation antidepressant vs placebo medication

Suicide‐related outcomes Timing of outcome assessment: end of treatment (6 to 12 weeks treatment duration) · patients with depressive disorders in children and adolescents

Second generation antidepressant may leads to higher suicide‐related outcome compared with placebo (by medication) (low certainty).

1 finding from 1 review

Newer generation antidepressants for depressive disorders in children and adolescents 2012 · Cochrane Headline outcomes only
RR 1.58 [1.02, 2.45]
17 studies · 3229 participants
Low

Second generation antidepressant vs placebo medication

Depressive symptoms · patients with depressive disorders in children and adolescents

1 finding from 1 review

Newer generation antidepressants for depressive disorders in children and adolescents 2012 · Cochrane Headline outcomes only
no estimate extracted
14 studies · 2490 participants
Low

Acupuncture vs medication

symptom severity (dichotomous outcome) Dichotomous measure of overall symptom severity1 · people with irritable bowel syndrome

Acupuncture may leads to higher symptom severity (dichotomous outcome) Dichotomous measure of… compared with pharmaceutical medications (low certainty).

1 finding from 1 review

Acupuncture for treatment of irritable bowel syndrome 2012 · Cochrane Headline outcomes only
RR 1.28 [1.12, 1.45]
5 studies · 449 participants
Low

INDIVIDUAL PSYCHODYNAMIC PSYCHOTHERAPY vs medication

Suicide · patients with schizophrenia and severe mental illness

INDIVIDUAL PSYCHODYNAMIC PSYCHOTHERAPY showed no clear difference in committed suicide by three years compared with MEDICATION (low certainty).

1 finding from 1 review

Individual psychodynamic psychotherapy and psychoanalysis for schizophrenia and severe mental illness 2001 · Cochrane Headline outcomes only
RR 0.52 [0.05, 5.56]
1 study · 94 participants
Low

INDIVIDUAL PSYCHODYNAMIC PSYCHOTHERAPY vs medication

Global impression: 1. Not able to be discharged (long term) · patients with schizophrenia and severe mental illness

INDIVIDUAL PSYCHODYNAMIC PSYCHOTHERAPY may leads to higher global impression: 1. Not able to be discharged (long term) compared with MEDICATION (low certainty).

1 finding from 1 review

Individual psychodynamic psychotherapy and psychoanalysis for schizophrenia and severe mental illness 2001 · Cochrane Headline outcomes only
RR 8.35 [2.03, 34.3]
1 study · 94 participants
Low

Antiviral prophylaxis vs placebo or no treatment

All symptomatic CMV disease · solid organ transplant recipients

Antiviral prophylaxis leads to lower CMV disease: all symptomatic CMV disease compared with placebo or no treatment (high certainty).

1 finding from 1 review

Antiviral medications for preventing cytomegalovirus disease in solid organ transplant recipients 2024 · Cochrane Headline outcomes only
RR 0.42 [0.34, 0.52]
19 studies · 1981 participants
High

Ganciclovir vs aciclovir

Death associated with CMV disease · solid organ transplant recipients

Ganciclovir showed no clear difference in death due to CMV disease compared with aciclovir (moderate certainty).

1 finding from 1 review

Antiviral medications for preventing cytomegalovirus disease in solid organ transplant recipients 2024 · Cochrane Headline outcomes only
RR 0.33 [0.07, 1.58]
6 studies · 832 participants
Moderate

Ganciclovir vs aciclovir

All‐cause death · solid organ transplant recipients

Ganciclovir showed no clear difference in all‐cause death compared with aciclovir (moderate certainty).

1 finding from 1 review

Antiviral medications for preventing cytomegalovirus disease in solid organ transplant recipients 2024 · Cochrane Headline outcomes only
RR 1.13 [0.82, 1.58]
8 studies · 1138 participants
Moderate