Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,793 questions · 1,866 findings · 339 reviews

No studies found 245 · 13.1%GRADE not reported 142 · 7.6%Very low 612 · 32.8%Low 513 · 27.5%Moderate 305 · 16.3%High 49 · 2.6%

CHLORPROMAZINE LOW DOSE (≤ 400 mg/day) vs MEDIUM DOSE (401 mg/day to 800 mg/day)

Adverse effects: any observed extrapyramidal symptoms ‐ short term (up to 6 months) · patients with schizophrenia

CHLORPROMAZINE LOW DOSE (≤ 400 mg/day) probably leads to lower adverse effects: extrapyramidal symptoms (unspecified extrapyramidal… compared with MEDIUM DOSE (401 mg/day to 800 mg/day) (moderate certainty).

1 finding from 1 review

Local corticosteroid injection (LCI) vs a control strategy (no treatment, placebo or waiting list controls)

Heel pain: VAS 0 to 100 (higher scores = worse pain) ‐ short‐term · Adults with plantar heel pain¹

Local steroid injection showed no clear difference in heel pain: VAS 0 to 100 (higher scores = worse pain) ‐ short‐term compared with placebo or no treatment control (low certainty).

1 finding from 1 review

Laparaoscopic radical prostatectomy and robotic‐assisted laparoscopic radical prostatectomy vs open radical prostatectomy

Overall rate of surgical complications

Laparaoscopic radical prostatectomy and robotic‐assisted… showed no clear difference in overall surgical complications (short‐term) compared with open radical prostatectomy (low certainty).

1 finding from 1 review

Probiotics used as adjuvants to conventional antifungal drugs vs conventional antifungal drugs

Clinical cure · non‐pregnant women with vulvovaginal candidiasis

Probiotics used as adjuvants to conventional antifungal drugs may leads to higher clinical cure rate (short‐term) compared with conventional antifungal drugs (low certainty).

1 finding from 1 review

Probiotics used as adjuvants to conventional antifungal drugs vs conventional antifungal drugs

Mycological cure · non‐pregnant women with vulvovaginal candidiasis

Probiotics used as adjuvants to conventional antifungal drugs may leads to higher mycological cure rate (short‐term) compared with conventional antifungal drugs (low certainty).

1 finding from 1 review