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What do systematic reviews say?

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Evidence found and GRADE certainty

990 questions · 1,028 findings · 131 reviews · Headline outcomes only

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No studies found 292 · 28.4%GRADE not reported 55 · 5.4%Very low 276 · 26.8%Low 240 · 23.3%Moderate 147 · 14.3%High 18 · 1.8%

Primary care physician alerting system vs primary care physician alerting system and a patient‐directed intervention (education and reminder to see their primary care physician)

Bone mineral density · General practitioners/family doctors involved in the management of patients with osteoporosis

Primary care physician alerting system showed no clear difference in bone mineral density1 compared with primary care physician alerting system and a patient‐directed… (moderate certainty).

1 finding from 1 review

Primary care physician alerting system vs primary care physician alerting system and a patient‐directed intervention (education and reminder to see their primary care physician)

Medication2 · General practitioners/family doctors involved in the management of patients with osteoporosis

Primary care physician alerting system showed no clear difference in medication2 compared with primary care physician alerting system and a patient‐directed… (moderate certainty).

1 finding from 1 review

SUPPORTIVE THERAPY vs PSYCHOEDUCATION

Service outcomes: Hospitalisation · patients with schizophrenia

It is very uncertain whether SUPPORTIVE THERAPY changes service outcomes: Hospitalisation compared with PSYCHOEDUCATION (very low certainty).

1 finding from 1 review

SUPPORTIVE THERAPY vs PSYCHOEDUCATION

Mental state: No clinically important improvement · patients with schizophrenia

It is very uncertain whether SUPPORTIVE THERAPY changes mental state. No clinically important improvement compared with PSYCHOEDUCATION (very low certainty).

1 finding from 1 review

SUPPORTIVE THERAPY vs PSYCHOEDUCATION

Leaving the study early · patients with schizophrenia

It is very uncertain whether SUPPORTIVE THERAPY changes leaving the study early compared with PSYCHOEDUCATION (very low certainty).

1 finding from 1 review