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What do systematic reviews say?

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Evidence found and GRADE certainty

1,304 questions · 1,352 findings · 210 reviews

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No studies found 230 · 17%GRADE not reported 163 · 12.1%Very low 269 · 19.9%Low 277 · 20.5%Moderate 291 · 21.5%High 122 · 9%

Hydromorphone vs fentanyl

Relief of pain · people with moderate to severe cancer pain

The review found no eligible studies for this question.

1 finding from 1 review

Hydromorphone vs fentanyl

Nausea · people with moderate to severe cancer pain

The review found no eligible studies for this question.

1 finding from 1 review

Hydromorphone vs fentanyl

Vomiting · people with moderate to severe cancer pain

The review found no eligible studies for this question.

1 finding from 1 review

Hydromorphone vs fentanyl

Dizziness · people with moderate to severe cancer pain

The review found no eligible studies for this question.

1 finding from 1 review

Hydromorphone vs oxycodone

Relief of pain · people with moderate to severe cancer pain

The review found no eligible studies for this question.

1 finding from 1 review

Hydromorphone vs fentanyl

Constipation · people with moderate to severe cancer pain

The review found no eligible studies for this question.

1 finding from 1 review

Hydromorphone vs fentanyl

Quality of life · people with moderate to severe cancer pain

The review found no eligible studies for this question.

1 finding from 1 review

Hydromorphone vs oxycodone

Nausea · people with moderate to severe cancer pain

It is very uncertain whether hydromorphone changes specific adverse events – nausea compared with oxycodone (very low certainty).

1 finding from 1 review

Hydromorphone vs oxycodone

Vomiting · people with moderate to severe cancer pain

It is very uncertain whether hydromorphone changes specific adverse events – vomiting compared with oxycodone (very low certainty).

1 finding from 1 review

Hydromorphone vs oxycodone

Dizziness · people with moderate to severe cancer pain

It is very uncertain whether hydromorphone changes specific adverse events – dizziness compared with oxycodone (very low certainty).

1 finding from 1 review

Hydromorphone vs oxycodone

Constipation · people with moderate to severe cancer pain

It is very uncertain whether hydromorphone changes specific adverse events – constipation compared with oxycodone (very low certainty).

1 finding from 1 review

Hydromorphone vs oxycodone

Quality of life · people with moderate to severe cancer pain

The review found no eligible studies for this question.

1 finding from 1 review

Hydromorphone vs morphine

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · people with moderate to severe cancer pain
1 finding from 1 review

Hydromorphone vs morphine

Relief of pain · people with moderate to severe cancer pain

It is very uncertain whether hydromorphone changes participant‐reported pain relief compared with morphine (very low certainty).

1 finding from 1 review

Summary of Findings Table ‐ Low vs moderate‐high nasal continuous positive airway pressure levels

Death or bronchopulmonary dysplasia at 36 weeks PMA · health problem or population

It is very uncertain whether summary of Findings Table ‐ Low changes death or BPD at 36 weeks PMA compared with moderate‐high nasal continuous positive airway pressure levels (very low certainty).

1 finding from 1 review

Summary of Findings Table ‐ Low vs moderate‐high nasal continuous positive airway pressure levels

BPD at 28 days · health problem or population

The review found no eligible studies for this question.

2 findings from 1 review

Summary of Findings Table ‐ Low vs moderate‐high nasal continuous positive airway pressure levels

BPD (36 weeks' PMA) · health problem or population

It is very uncertain whether summary of Findings Table ‐ Low changes BPD, defined as supplemental oxygen or positive pressure support use… compared with moderate‐high nasal continuous positive airway pressure levels (very low certainty).

1 finding from 1 review

Summary of Findings Table ‐ Low vs moderate‐high nasal continuous positive airway pressure levels

Treatment failure or need for mechanical ventilation · health problem or population

It is very uncertain whether summary of Findings Table ‐ Low changes treatment failure or need for mechanical ventilation compared with moderate‐high nasal continuous positive airway pressure levels (very low certainty).

2 findings from 1 review

Summary of Findings Table ‐ Low vs moderate‐high nasal continuous positive airway pressure levels

Mortality before hospital discharge · health problem or population

It is very uncertain whether summary of Findings Table ‐ Low changes mortality, by hospital discharge compared with moderate‐high nasal continuous positive airway pressure levels (very low certainty).

2 findings from 1 review

Summary of Findings Table ‐ Low vs moderate‐high nasal continuous positive airway pressure levels

Bronchopulmonary dysplasia/chronic lung disease · health problem or population

It is very uncertain whether summary of Findings Table ‐ Low changes BPD, defined as supplemental oxygen or positive pressure support use… compared with moderate‐high nasal continuous positive airway pressure levels (very low certainty).

1 finding from 1 review