Hydromorphone vs oxycodone: Constipation
- Population
- people with moderate to severe cancer pain
- Intervention
- Hydromorphone
- Comparison
- oxycodone
- Outcome
- Constipation
It is very uncertain whether hydromorphone changes specific adverse events – constipation compared with oxycodone (very low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Hydromorphone vs oxycodone Specific adverse events – constipation · people with moderate to severe cancer pain It is very uncertain whether hydromorphone changes specific adverse events – constipation compared with oxycodone (very low certainty). Hydromorphone for cancer pain (2021) · Cochrane Headline outcomes only | RR 0.92 [0.72, 1.19] | 3 studies · 622 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Hydromorphone for cancer pain 2021 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
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How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.