Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,156 questions · 1,179 findings · 198 reviews · Headline outcomes only

No studies found 250 · 21.2%GRADE not reported 43 · 3.6%Very low 236 · 20%Low 395 · 33.5%Moderate 208 · 17.6%High 47 · 4%

Surgery vs oral medication

Control of bleeding (cure or improvement to acceptable level) At 2 years · women with heavy menstrual bleeding

Surgery probably leads to higher control of bleeding (cure or improvement to acceptable level) At 4… compared with oral medication (moderate certainty).

3 findings from 1 review

Surgery vs oral medication

Overall satisfaction with treatment At 5 years · women with heavy menstrual bleeding

It is very uncertain whether surgery changes overall satisfaction with treatment At 5 years compared with oral medication (very low certainty).

1 finding from 1 review

Intervention not reported

Adverse outcome: unintended adverse events attributable to the intervention Multimodal/complex intervention, ATCS Plus, IVR, unidirectional versus various controls · patients with various conditions or at risk of low adherence to medication or laboratory tests

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Knowledge [questionnaire (scored out of 80), measured immediately post‐intervention] · people with a health condition or nominally 'well' considering real or hypothetical clinical trial participation in cancer or psychiatric…

The intervention may leads to lower knowledge [questionnaire (scored out of 80), measured immediately… (low certainty).

1 finding from 1 review

Intervention not reported

Knowledge [scored correct answer to single question, measured immediately post‐intervention] · people with a health condition or nominally 'well' considering real or hypothetical clinical trial participation in cancer or psychiatric…

The intervention showed no clear difference in knowledge [scored correct answer to single question, measured… (low certainty).

1 finding from 1 review

Intervention not reported

Satisfaction with the information provided [single question, measured immediately post‐intervention] · people with a health condition or nominally 'well' considering real or hypothetical clinical trial participation in cancer or psychiatric…

The intervention may leads to higher satisfaction with the information provided [single question,… (low certainty).

1 finding from 1 review