Findings

What do systematic reviews say?

728 questions · 764 findings · 107 reviews

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No studies found 194 · 25.4%GRADE not reported 47 · 6.2%Very low 212 · 27.7%Low 194 · 25.4%Moderate 99 · 13%High 18 · 2.4%

Sclerotherapy vs sclerotherapy with different substances

QoL · participants with varicose veinsb

The review found no eligible studies for this question.

1 finding from 1 review

Injection sclerotherapy for varicose veins 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Sclerotherapy vs sclerotherapy with different substances

Persistence of symptoms · participants with varicose veinsb

The review found no eligible studies for this question.

1 finding from 1 review

Injection sclerotherapy for varicose veins 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Sclerotherapy vs sclerotherapy with different substances

Recurrent varicose veins · participants with varicose veinsb

The review found no eligible studies for this question.

1 finding from 1 review

Injection sclerotherapy for varicose veins 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Foam sclerotherapy vs placebo

Residual varicose veins · participants with varicose veinsa

It is very uncertain whether foam sclerotherapy changes residual varicose veins compared with placebo (very low certainty).

1 finding from 1 review

Injection sclerotherapy for varicose veins 2021 · Cochrane Headline outcomes only
RR 0.19 [0.13, 0.29]
2 studies · 225 participants
Very low

Foam sclerotherapy vs placebo

QoL · participants with varicose veinsa

1 finding from 1 review

Injection sclerotherapy for varicose veins 2021 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 299 participants
Very low

Foam sclerotherapy vs placebo

Persistence of symptoms · participants with varicose veinsa

1 finding from 1 review

Injection sclerotherapy for varicose veins 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 223 participants
Low

Foam sclerotherapy vs placebo

Recurrent varicose veins · participants with varicose veinsa

The review found no eligible studies for this question.

1 finding from 1 review

Injection sclerotherapy for varicose veins 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Foam sclerotherapy vs foam sclerotherapy

Cosmetic appearance · participants with varicose veinsa

It is very uncertain whether foam sclerotherapy changes cosmetic appearance (self‐described cosmetic improvement) compared with foam sclerotherapy (very low certainty).

1 finding from 1 review

Injection sclerotherapy for varicose veins 2021 · Cochrane Headline outcomes only
RR 1.11 [0.84, 1.47]
1 study · 80 participants
Very low

Foam sclerotherapy vs foam sclerotherapy

Number of thromboembolic complications · participants with varicose veinsa

It is very uncertain whether foam sclerotherapy changes complications ‐ thromboembolic compared with foam sclerotherapy (very low certainty).

1 finding from 1 review

Injection sclerotherapy for varicose veins 2021 · Cochrane Headline outcomes only
RR 1.47 [0.41, 5.33]
3 studies · 371 participants
Very low

Foam sclerotherapy vs foam sclerotherapy

Residual varicose veins · participants with varicose veinsa

Foam sclerotherapy showed no clear difference in residual varicose veins compared with foam sclerotherapy (moderate certainty).

1 finding from 1 review

Injection sclerotherapy for varicose veins 2021 · Cochrane Headline outcomes only
RR 0.67 [0.43, 1.04]
3 studies · 371 participants
Moderate

Assisted hatching vs no assisted hatching

Live birth rate per woman · women undergoing assisted reproduction

Assisted hatching showed no clear difference in live births per woman randomised compared with no assisted hatching (low certainty).

1 finding from 1 review

Assisted hatching on assisted conception (in vitro fertilisation (IVF) and intracytoplasmic sperm injection (ICSI)) 2021 · Cochrane Headline outcomes only
OR 1.09 [0.92, 1.29]
14 studies · 2849 participants
Low

Assisted hatching vs no assisted hatching

Multiple pregnancy rate · women undergoing assisted reproduction

Assisted hatching may leads to higher multiple pregnancy rate per woman randomised compared with no assisted hatching (low certainty).

1 finding from 1 review

Assisted hatching on assisted conception (in vitro fertilisation (IVF) and intracytoplasmic sperm injection (ICSI)) 2021 · Cochrane Headline outcomes only
OR 1.38 [1.13, 1.68]
18 studies · 4308 participants
Low

Assisted hatching vs no assisted hatching

Clinical pregnancy rate · women undergoing assisted reproduction

Assisted hatching may leads to higher clinical pregnancy rate per woman randomised compared with no assisted hatching (low certainty).

1 finding from 1 review

Assisted hatching on assisted conception (in vitro fertilisation (IVF) and intracytoplasmic sperm injection (ICSI)) 2021 · Cochrane Headline outcomes only
OR 1.2 [1.09, 1.33]
39 studies · 7249 participants
Low

Assisted hatching vs no assisted hatching

Miscarriage · women undergoing assisted reproduction

It is very uncertain whether assisted hatching changes miscarriage rate per woman randomised compared with no assisted hatching (very low certainty).

1 finding from 1 review

Assisted hatching on assisted conception (in vitro fertilisation (IVF) and intracytoplasmic sperm injection (ICSI)) 2021 · Cochrane Headline outcomes only
OR 1.13 [0.82, 1.56]
17 studies · 2810 participants
Very low

Autologous blood or PRP vs placebo at 3 months' follow‐up

Pain (VAS, PRTEE) translated to 0 to 10, where 0 is no pain · lateral elbow pain

1 finding from 1 review

Autologous blood and platelet‐rich plasma injection therapy for lateral elbow pain 2021 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 523 participants
Moderate

Autologous blood or PRP vs placebo at 3 months' follow‐up

Disability DASH scale. Scale from: 0 to 100. ( · lateral elbow pain

1 finding from 1 review

Autologous blood and platelet‐rich plasma injection therapy for lateral elbow pain 2021 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 502 participants
Moderate

Autologous blood or PRP vs placebo at 3 months' follow‐up

Treatment success (> 25% improvement in pain or function) · lateral elbow pain

It is very uncertain whether autologous blood or PRP changes treatment success (> 25% improvement in pain or function) compared with placebo at 3 months' follow‐up (very low certainty).

1 finding from 1 review

Autologous blood and platelet‐rich plasma injection therapy for lateral elbow pain 2021 · Cochrane Headline outcomes only
RR 1 [0.83, 1.19]
4 studies · 372 participants
Very low

Autologous blood or PRP vs placebo at 3 months' follow‐up

Health‐related Quality of Life Not measured · lateral elbow pain

1 finding from 1 review

Autologous blood and platelet‐rich plasma injection therapy for lateral elbow pain 2021 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Autologous blood or PRP vs placebo at 3 months' follow‐up

Relief of pain · lateral elbow pain

1 finding from 1 review

Autologous blood and platelet‐rich plasma injection therapy for lateral elbow pain 2021 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Autologous blood or PRP vs placebo at 3 months' follow‐up

Withdrawals due to adverse events · lateral elbow pain

It is very uncertain whether autologous blood or PRP changes withdrawal due to adverse events Â compared with placebo at 3 months' follow‐up (very low certainty).

1 finding from 1 review

Autologous blood and platelet‐rich plasma injection therapy for lateral elbow pain 2021 · Cochrane Headline outcomes only
RR 0.32 [0.03, 2.92]
1 study · 80 participants
Very low