Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,097 questions · 3,266 findings · 631 reviews

No studies found 430 · 13.2%GRADE not reported 193 · 5.9%Very low 995 · 30.5%Low 904 · 27.7%Moderate 591 · 18.1%High 153 · 4.7%

Higher polyunsaturated fatty acid (PUFA) vs lower PUFA

Atrial fibrillation and arrhythmias · people with or without existing cardiovascular disease, men and women

It is very uncertain whether higher polyunsaturated fatty acid (PUFA) changes atrial fibrillation and arrhythmias compared with lower PUFA (very low certainty).

1 finding from 1 review

Higher BP target (< 150‐160/95‐105 mmHg) vs lower BP target (< 140/90 mmHg)

Serious adverse events: cardiovascular events · older adults with primary hypertension

Higher BP target (< 150‐160/95‐105 mmHg) showed no clear difference in cardiovascular serious adverse events compared with lower BP target (< 140/90 mmHg) (low certainty).

1 finding from 1 review

High‐intensity brief text messaging (SMS) vs low‐intensity brief text messaging

Documenting of matched pregnancy outcome data · Community health care workers, known as Health Surveillance Assistants (HSAs) (n = 156) associated with 30 health facilities.

High‐intensity brief text messaging (SMS) showed no clear difference in documenting of matched pregnancy outcome data compared with low‐intensity brief text messaging (low certainty).

1 finding from 1 review

High‐intensity brief text messaging (SMS) vs low‐intensity brief text messaging

Functioning of the RHIS · Community health care workers, known as Health Surveillance Assistants (HSAs) (n = 156) associated with 30 health facilities.

The review found no eligible studies for this question.

1 finding from 1 review

High‐intensity brief text messaging (SMS) vs low‐intensity brief text messaging

Health provider outcomes · Community health care workers, known as Health Surveillance Assistants (HSAs) (n = 156) associated with 30 health facilities.

The review found no eligible studies for this question.

1 finding from 1 review

Vitamin D (higher dose) + micronutrient(s) vs vitamin D (lower dose) + micronutrient(s)

Adverse effect: hypercalciuria As defined by trialists Time frame: 3 months · children under 5 years of age

Vitamin D (higher dose) + micronutrient(s) showed no clear difference in adverse effect: hypercalciuria As defined by trialists Time frame: 3… compared with vitamin D (lower dose) + micronutrient(s) (low certainty).

1 finding from 1 review

Vitamin D (higher dose) + micronutrient(s) vs vitamin D (lower dose) + micronutrient(s)

Hypercalcaemia · children under 5 years of age

Vitamin D (higher dose) + micronutrient(s) showed no clear difference in adverse effect: hypercalcaemia As defined by trialists Time frame:… compared with vitamin D (lower dose) + micronutrient(s) (moderate certainty).

1 finding from 1 review