Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,340 questions · 1,512 findings · 205 reviews

No studies found 317 · 21%GRADE not reported 358 · 23.7%Very low 356 · 23.5%Low 271 · 17.9%Moderate 173 · 11.4%High 37 · 2.4%

Phacoemulsification + supraciliary microstent surgery vs phacoemulsification alone

Proportion of participants who were medication‐free (not using eye drops) medium‐term · people with open‐angle glaucoma

Phacoemulsification + supraciliary microstent surgery probably leads to higher proportion of participants who were medication‐free (not using… compared with phacoemulsification alone (moderate certainty).

1 finding from 1 review

Phacoemulsification + supraciliary microstent surgery vs phacoemulsification alone

Mean change in unmedicated IOP24 months (medium‐term) · people with open‐angle glaucoma

Phacoemulsification + supraciliary microstent surgery showed no clear difference in mean change in unmedicated IOP24 months (medium‐term) compared with phacoemulsification alone (high certainty).

1 finding from 1 review

Phacoemulsification + supraciliary microstent surgery vs phacoemulsification alone

Mean change in daily IOP‐lowering medicationsat 24 months (medium‐term) · people with open‐angle glaucoma

Phacoemulsification + supraciliary microstent surgery showed no clear difference in mean change in daily IOP‐lowering medicationsat 24 months… compared with phacoemulsification alone (moderate certainty).

1 finding from 1 review

Phacoemulsification + supraciliary microstent surgery vs phacoemulsification alone

Proportion of participants who required further glaucoma surgery, including laser · people with open‐angle glaucoma

Phacoemulsification + supraciliary microstent surgery showed no clear difference in proportion of participants who required further glaucoma surgeryat… compared with phacoemulsification alone (low certainty).

1 finding from 1 review

Phacoemulsification + supraciliary microstent surgery vs phacoemulsification alone

Proportion of participants experiencing postoperative complicationsover 24 months (medium‐term) · people with open‐angle glaucoma

Phacoemulsification + supraciliary microstent surgery showed no clear difference in proportion of participants experiencing postoperative… compared with phacoemulsification alone (moderate certainty).

1 finding from 1 review

Laparoscopic pyloromyotomy vs open pyloromyotomy

Postoperative wound infection or abscess formation · infants (< 1 year of age) with hypertrophic pyloric stenosis

It is very uncertain whether laparoscopic pyloromyotomy changes postoperative wound infection or abscess formation compared with open pyloromyotomy (very low certainty).

1 finding from 1 review

Antibiotic prophylaxis vs placebo

Wound infection · prevention of postoperative wound infection in adults undergoing open elective inguinal or femoral hernioplasty hernia repair

It is very uncertain whether antibiotic prophylaxis changes all wound infections (SSSI + DSSI) compared with placebo (very low certainty).

2 findings from 1 review

Antibiotic prophylaxis vs placebo

DSSI · prevention of postoperative wound infection in adults undergoing open elective inguinal or femoral hernioplasty hernia repair

Antibiotic prophylaxis showed no clear difference in DSSI compared with placebo (moderate certainty).

1 finding from 1 review

Antibiotic prophylaxis vs placebo

DSSI ‐ low infection risk environment · prevention of postoperative wound infection in adults undergoing open elective inguinal or femoral hernioplasty hernia repair

Antibiotic prophylaxis showed no clear difference in DSSI ‐ low infection risk environment compared with placebo (moderate certainty).

1 finding from 1 review

Antibiotic prophylaxis vs placebo

DSSI ‐ high infection risk environment · prevention of postoperative wound infection in adults undergoing open elective inguinal or femoral hernioplasty hernia repair

Antibiotic prophylaxis showed no clear difference in DSSI ‐ high infection risk environment compared with placebo (low certainty).

1 finding from 1 review

Antibiotic prophylaxis vs placebo

All wound infections (SSSI + DSSI) ‐ low infection risk environment · prevention of postoperative wound infection in adults undergoing open elective inguinal or femoral hernioplasty hernia repair

It is very uncertain whether antibiotic prophylaxis changes all wound infections (SSSI + DSSI) ‐ low infection risk environment compared with placebo (very low certainty).

2 findings from 1 review

Antibiotic prophylaxis vs placebo

All wound infections (SSSI + DSSI) ‐ high infection risk environment · prevention of postoperative wound infection in adults undergoing open elective inguinal or femoral hernioplasty hernia repair

It is very uncertain whether antibiotic prophylaxis changes all wound infections (SSSI + DSSI) ‐ high infection risk environment compared with placebo (very low certainty).

2 findings from 1 review