Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · sickle cell disease
N‐acetylcysteine (1200 mg) showed no clear difference in severity of pain (maximum pain intensity on pain days) compared with placebo (low certainty).
1 finding from 1 review
Frequency of hospitalization (number of days in hospital) · sickle cell disease
It is very uncertain whether L‐arginine changes frequency of hospitalization (number of days in hospital) compared with placebo (very low certainty).
1 finding from 1 review
Energy intake · adults
1 finding from 1 review
Duration of cold symptoms (days) · adults and children without colds
1 finding from 1 review
Duration of cold symptoms (days) · adults and children with colds and/or upper respiratory infections
1 finding from 1 review
Intervention not reported
Intended and unintended consequences: social and institutional consequences ‐ days of absences avoided
1 finding from 1 review
no estimate extracted
Studies not reported
Moderate
Length of hospital stay · adults with uncomplicated appendicitis
It is very uncertain whether antibiotics changes length of hospital stay (days) compared with surgery (very low certainty).
1 finding from 1 review
Number of drinks per day ‐ total · stopping or reducing alcohol consumption during pregnancy
1 finding from 1 review
Clinical remission · people with mild‐to‐moderate disease (Rachmilewitz index) or active disease (SCCAI score of 4 to 10)
It is very uncertain whether prebiotics changes clinical remission (14 days) compared with placebo (very low certainty).
1 finding from 1 review
Clinical improvement (partial Mayo score) (60 days) · people with histologically confirmed diagnosis of ulcerative colitis in remission
1 finding from 1 review
Health‐related quality of life (timeframe not reported) ‐ IBDQ ‐ Symptoms‐guided diet · people with histologically confirmed diagnosis of ulcerative colitis in remission
1 finding from 1 review
Clinical improvement (Rachmilewitz index) (14 days) · people with mild‐to‐moderate disease (Rachmilewitz index) or active disease (SCCAI score of 4 to 10)
1 finding from 1 review
Withdrawals due to adverse events · people with histologically confirmed diagnosis of ulcerative colitis in remission
It is very uncertain whether prebiotics changes withdrawals due to adverse events (60 days to 6 months) compared with placebo (very low certainty).
1 finding from 1 review
Withdrawals due to adverse events · people with mild‐to‐moderate disease (Rachmilewitz index) or active disease (SCCAI score of 4 to 10)
It is very uncertain whether prebiotics changes withdrawals due to adverse events (14 days to 2 or 3 months) compared with placebo (very low certainty).
1 finding from 1 review
COVID‐related absenteeism from work Days absent per 1000 working days (over 13‐week · school staff
Test‐based attendance showed no clear difference in COVID‐related absenteeism from work Days absent per 1000 working… compared with routine isolation after contact with a SARS‐CoV‐2‐positive person (low certainty).
1 finding from 1 review
All‐cause mortality – at 28 to 30 days, or in‐hospital · people with confirmed COVID‐19
It is very uncertain whether favipiravir changes all‐cause mortality – at 28 to 30 days, or in‐hospital compared with no treatment, supportive treatment, or other antiviral treatment (very low certainty).
1 finding from 1 review
Adverse events (reported in the first 7 days after the procedure) · children with acute postoperative pain
1 finding from 1 review
Adverse events (reported in the first 7 days after the procedure) · children with acute postoperative pain
Ibuprofen probably leads to lower adverse events (reported in the first 7 days after the procedure) compared with morphine (moderate certainty).
1 finding from 1 review
Adverse events (reported in the first 7 days after the procedure) · children with acute postoperative pain
1 finding from 1 review
Adverse events (reported in the first 7 days after the procedure) · children with acute postoperative pain
Ibuprofen showed no clear difference in adverse events (reported in the first 7 days after the procedure) compared with placebo (low certainty).
1 finding from 1 review