Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,123 questions · 2,188 findings · 243 reviews

No studies found 493 · 22.5%GRADE not reported 160 · 7.3%Very low 600 · 27.4%Low 474 · 21.7%Moderate 364 · 16.6%High 97 · 4.4%

Antibiotic prophylaxis vs no treatment or placebo

Wound infection (episiotomy dehiscence) · Women who had normal vaginal births

It is very uncertain whether routine antibiotic prophylaxis changes wound infection (episiotomy dehiscence) compared with no treatment or placebo (very low certainty).

1 finding from 1 review

Summary of findings: oral steroids plus antibiotic vs control plus antibiotic

Adverse effects [2 weeks to 6 months] · Children with otitis media with effusion

Summary of findings: oral steroids plus antibiotic showed no clear difference in adverse effects [2 weeks to 6 months] compared with control plus antibiotic (low certainty).

1 finding from 1 review

Summary of findings: oral steroids plus antibiotic vs control plus antibiotic

Hearing loss · Children with otitis media with effusion

Summary of findings: oral steroids plus antibiotic showed no clear difference in hearing loss [2 months]1 compared with control plus antibiotic (moderate certainty).

1 finding from 1 review

Summary of findings: oral steroids plus antibiotic vs control plus antibiotic

OME resolution at short‐term · Children with otitis media with effusion

Summary of findings: oral steroids plus antibiotic leads to higher OME resolution at short‐term compared with control plus antibiotic (high certainty).

1 finding from 1 review