Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

781 questions · 1,089 findings · 92 reviews · Dental caries

No studies found 77 · 7.1%GRADE not reported 781 · 71.7%Very low 86 · 7.9%Low 97 · 8.9%Moderate 38 · 3.5%High 10 · 0.9%

Dementia (any type or severity) vs Older people without dementia

Dental caries: prevalence of root caries · Older people (aged 60 years or older) with dementia

Root caries was higher in older people with dementia (0.6 to 4.9) than without (0.3 to 1.7), described as significantly more common but not pooled (ungraded).

1 finding from 1 review

Resin-based fissure sealant (2nd/3rd/4th generation) vs No sealant (control/no treatment)

Dentine caries in permanent molars (24 months) · Children and adolescents (general population, aged under 20 years)

Resin-based fissure sealant (2nd/3rd/4th generation) probably leads to lower dentine caries in permanent molars (24 months) compared with no sealant (control/no treatment) (moderate certainty).

1 finding from 1 review

Dementia (any type or severity) vs Older people without dementia

Edentulousness (prevalence) · Older people (aged 60 years or older) with dementia

Edentulousness was similar in older people with and without dementia, with wide overlapping ranges across studies; no meta-analysis was performed (ungraded).

1 finding from 1 review

Dementia (any type or severity) vs Older people without dementia

Orofacial pain (prevalence) · Older people (aged 60 years or older) with dementia

Orofacial pain prevalence was similar in older people with dementia (7.4 to 21.7%) and without dementia (6.7 to 18.5%), based on few studies; no meta-analysis was performed (ungraded).

1 finding from 1 review

Dementia (any type or severity) vs Older people without dementia

Coronal caries (mean number) · Older people (aged 60 years or older) with dementia

Coronal caries was higher in older people with dementia (0.1 to 2.9) than without (0.0 to 1.0), described as significantly more common but not pooled (ungraded).

1 finding from 1 review

ART using composite resin vs Conventional treatment using composite resin

Restoration failure (primary dentition) · Children with carious primary teeth

It is very uncertain whether ART using composite resin changes restoration failure (primary dentition) compared with conventional treatment using composite resin (very low certainty).

1 finding from 1 review

ART using resin-modified glass ionomer cement (RM-GIC) vs Conventional treatment using RM-GIC

Restoration failure (primary dentition) · Older adults with root caries in permanent (mature) teeth (mean age 75 years)

The review found no eligible studies for this question.

1 finding from 1 review

Glass ionomer-based sealant vs Resin-based sealant

Dentine caries in permanent molars (24 months) · Children and adolescents (general population, aged under 20 years)
1 finding from 1 review

Dementia (any type or severity) vs Older people without dementia

Number of teeth · Older people (aged 60 years or older) with dementia

The number of teeth present was comparable between older people with and without dementia; no meta-analysis was performed (ungraded).

1 finding from 1 review

ART using resin-modified glass ionomer cement (RM-GIC) vs Conventional treatment using RM-GIC

Restoration failure (permanent, mature dentition; root surfaces) · Older adults with root caries in permanent (mature) teeth (mean age 75 years)

It is very uncertain whether ART using resin-modified glass ionomer cement (RM-GIC) changes restoration failure (permanent, mature dentition; root surfaces) compared with conventional treatment using RM-GIC (very low certainty).

1 finding from 1 review

Laser (Er:YAG, Er,Cr:YSGG, or Nd:YAG) vs Conventional mechanical caries removal (standard drill; handpiece with a bur)

Marginal integrity of restoration · Children, adolescents and adults with caries in deciduous and permanent teeth (age 3.5 to 84 years)

Laser (Er:YAG, Er,Cr:YSGG, or Nd:YAG) showed no clear difference in marginal integrity of restorations compared with conventional mechanical caries removal (standard drill; handpiece…; GRADE not reported.

3 findings from 1 review

Laser (Er:YAG, Er,Cr:YSGG, or Nd:YAG) vs Conventional mechanical caries removal (standard drill; handpiece with a bur)

Participant discomfort (vibration, smell, noise) · Children, adolescents and adults with caries in deciduous and permanent teeth (age 3.5 to 84 years)
1 finding from 1 review
  • Lasers for caries removal in deciduous and permanent teeth 2016 · Cochrane All outcomes
    during treatment
    Five studies reported participant discomfort (Belcheva 2014; Evans 2000; Hadley 2000; Keller 1998; Liu 2006). Keller 1998 (90 adults): discomfort significantly lower with laser (Analysis 1.6). Hadley 2000 (66 adults):…
    5 studies
    GRADE not reported

Laser (Er:YAG, Er,Cr:YSGG, or Nd:YAG) vs Conventional mechanical caries removal (standard drill; handpiece with a bur)

Pulpal inflammation or necrosis · Children, adolescents and adults with caries in deciduous and permanent teeth (age 3.5 to 84 years)

It is very uncertain whether laser (Er:YAG, Er,Cr:YSGG, or Nd:YAG) changes pulpal inflammation or necrosis compared with conventional mechanical caries removal (standard drill; handpiece… (very low certainty).

3 findings from 1 review