Question · asked by 1 review

Resin-based fissure sealant (2nd/3rd/4th generation) vs No sealant (control/no treatment): Dentine caries in permanent molars (24 months)

Resin-based fissure sealant (2nd/3rd/4th generation) probably leads to lower dentine caries in permanent molars (24 months) compared with no sealant (control/no treatment) (moderate certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Resin-based fissure sealant (2nd/3rd/4th generation) vs No sealant (control/no treatment)
Dentine caries in permanent molars (24 months) · Children and adolescents (general population, aged under 20 years) · 24 months
Resin-based fissure sealant (2nd/3rd/4th generation) probably leads to lower dentine caries in permanent molars (24 months) compared with no sealant (control/no treatment) (moderate certainty).
Pit and fissure sealants for preventing dental decay in permanent teeth (2017) · Cochrane All outcomes
OR 0.12 [0.08, 0.19]7 studies · 1322 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Pit and fissure sealants for preventing dental decay in permanent teeth
2017 · Cochrane All outcomes
2016-08list not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.