Resin-based fissure sealant (2nd/3rd/4th generation) vs No sealant (control/no treatment): Dentine caries in permanent molars (24 months)
Resin-based fissure sealant (2nd/3rd/4th generation) probably leads to lower dentine caries in permanent molars (24 months) compared with no sealant (control/no treatment) (moderate certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Resin-based fissure sealant (2nd/3rd/4th generation) vs No sealant (control/no treatment) Dentine caries in permanent molars (24 months) · Children and adolescents (general population, aged under 20 years) · 24 months Resin-based fissure sealant (2nd/3rd/4th generation) probably leads to lower dentine caries in permanent molars (24 months) compared with no sealant (control/no treatment) (moderate certainty). Pit and fissure sealants for preventing dental decay in permanent teeth (2017) · Cochrane All outcomes | OR 0.12 [0.08, 0.19] | 7 studies · 1322 participants | Moderate |
Resin-based fissure sealant (2nd/3rd/4th generation) vs No sealant (control/no treatment) Dentine caries in permanent molars (24 months) · Children and adolescents (general population, aged under 20 years) · 24 months Resin-based fissure sealant (2nd/3rd/4th generation) probably leads to lower dentine caries in permanent molars (24 months) compared with no sealant (control/no treatment) (moderate certainty). Pit and fissure sealants for preventing dental decay in permanent teeth (2013) · Cochrane All outcomesearlier version CD001830.PUB4, superseded | OR 0.12 [0.07, 0.19] | 6 studies · 1066 participants | Moderate |
Resin-based fissure sealant (2nd/3rd/4th generation) vs No sealant (control/no treatment) Dentine caries in permanent molars (24 months) · Children and adolescents (general population, aged under 20 years) · 24 months Resin-based fissure sealant (2nd/3rd/4th generation) led to lower dentine caries in permanent molars (24 months) compared with no sealant (control/no treatment); GRADE not reported. Pit and fissure sealants for preventing dental decay in permanent teeth (2008) · Cochrane All outcomesearlier version CD001830.PUB3, superseded | RR 0.22 [0.15, 0.34] | 3 studies | GRADE not reported |
Resin-based fissure sealant (2nd/3rd/4th generation) vs No sealant (control/no treatment) Dentine caries in permanent molars (24 months) · Children and adolescents (general population, aged under 20 years) · 24 months Resin-based fissure sealant (2nd/3rd/4th generation) led to lower dentine caries in permanent molars (24 months) compared with no sealant (control/no treatment); GRADE not reported. Pit and fissure sealants for preventing dental decay in permanent teeth (2004) · Cochrane All outcomesearlier version CD001830.PUB2, superseded | RR 0.24 [0.20, 0.30] | 3 studies | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Pit and fissure sealants for preventing dental decay in permanent teeth 2017 · Cochrane All outcomes | 2016-08 | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.