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Evidence found and GRADE certainty

677 questions · 719 findings · 133 reviews

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No studies found 153 · 21.3%GRADE not reported 54 · 7.5%Very low 164 · 22.8%Low 199 · 27.7%Moderate 119 · 16.6%High 30 · 4.2%

GM‐CSF‐supplemented culture media vs culture media not supplemented with GM‐CSF

Live birth or ongoing pregnancy · women undergoing assisted reproduction

GM‐CSF‐supplemented culture media showed no clear difference in live birth or ongoing pregnancy compared with culture media not supplemented with GM‐CSF (low certainty).

1 finding from 1 review

GM‐CSF‐supplemented culture media vs culture media not supplemented with GM‐CSF

Miscarriage · women undergoing assisted reproduction

GM‐CSF‐supplemented culture media showed no clear difference in miscarriage compared with culture media not supplemented with GM‐CSF (low certainty).

1 finding from 1 review

GM‐CSF‐supplemented culture media vs culture media not supplemented with GM‐CSF

Clinical pregnancy · women undergoing assisted reproduction

GM‐CSF‐supplemented culture media showed no clear difference in clinical pregnancy compared with culture media not supplemented with GM‐CSF (low certainty).

1 finding from 1 review

GM‐CSF‐supplemented culture media vs culture media not supplemented with GM‐CSF

Multiple gestation · women undergoing assisted reproduction

It is very uncertain whether GM‐CSF‐supplemented culture media changes multiple gestation compared with culture media not supplemented with GM‐CSF (very low certainty).

1 finding from 1 review

GM‐CSF‐supplemented culture media vs culture media not supplemented with GM‐CSF

Preterm birth · women undergoing assisted reproduction

It is very uncertain whether GM‐CSF‐supplemented culture media changes preterm birth compared with culture media not supplemented with GM‐CSF (very low certainty).

1 finding from 1 review

GM‐CSF‐supplemented culture media vs culture media not supplemented with GM‐CSF

Birth defects · women undergoing assisted reproduction

GM‐CSF‐supplemented culture media showed no clear difference in birth defects compared with culture media not supplemented with GM‐CSF (low certainty).

1 finding from 1 review

GM‐CSF‐supplemented culture media vs culture media not supplemented with GM‐CSF

Aneuploidy · women undergoing assisted reproduction

GM‐CSF‐supplemented culture media showed no clear difference in aneuploidy compared with culture media not supplemented with GM‐CSF (low certainty).

1 finding from 1 review

Decompressive craniectomy vs medical treatment

Mortality at 6 months · patients > 12 months of age with a severe traumatic brain injury and in a coma (post‐resuscitation GOS score ≤ 8 points) with raised,…

Decompressive craniectomy probably leads to lower mortality at 6 months compared with medical treatment only (moderate certainty).

1 finding from 1 review

Decompressive craniectomy vs medical treatment

Mortality at 12 months · patients > 12 months of age with a severe traumatic brain injury and in a coma (post‐resuscitation GOS score ≤ 8 points) with raised,…

Decompressive craniectomy leads to lower mortality at 12 months compared with medical treatment only (high certainty).

1 finding from 1 review

Decompressive craniectomy vs medical treatment

'Unfavorable outcome' as per original Cochrane protocol at 6 months · patients > 12 months of age with a severe traumatic brain injury and in a coma (post‐resuscitation GOS score ≤ 8 points) with raised,…

Decompressive craniectomy may leads to higher 'Unfavorable outcome' as per original Cochrane protocol at 6 months compared with medical treatment only (low certainty).

1 finding from 1 review

Decompressive craniectomy vs medical treatment

'Unfavorable outcome' as per original Cochrane protocol ‐ at 12 months · patients > 12 months of age with a severe traumatic brain injury and in a coma (post‐resuscitation GOS score ≤ 8 points) with raised,…

Decompressive craniectomy showed no clear difference in 'Unfavorable outcome' as per original Cochrane protocol ‐ at 12 months compared with medical treatment only (high certainty).

1 finding from 1 review

Decompressive craniectomy vs medical treatment

Changes in ICP from randomization up to 48 h · patients > 12 months of age with a severe traumatic brain injury and in a coma (post‐resuscitation GOS score ≤ 8 points) with raised,…

Decompressive craniectomy showed no clear difference in changes in ICP from randomization up to 48 h compared with medical treatment only (moderate certainty).

1 finding from 1 review