Question · asked by 1 review

GM‐CSF‐supplemented culture media vs culture media not supplemented with GM‐CSF: Miscarriage

GM‐CSF‐supplemented culture media showed no clear difference in miscarriage compared with culture media not supplemented with GM‐CSF (low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
GM‐CSF‐supplemented culture media vs culture media not supplemented with GM‐CSF
Miscarriage · women undergoing assisted reproduction
GM‐CSF‐supplemented culture media showed no clear difference in miscarriage compared with culture media not supplemented with GM‐CSF (low certainty).
GM‐CSF (granulocyte macrophage colony‐stimulating factor) supplementation in culture media for women… (2020) · Cochrane Headline outcomes only
OR 0.75 [0.41, 1.36]2 studies · 1432 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
GM‐CSF (granulocyte macrophage colony‐stimulating factor) supplementation in culture media for women undergoing assisted reproduction
2020 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.