Laboratory‐confirmed leptospirosis · farmworkers, soldiers, and people in endemic areas
It is very uncertain whether summary of findings table ‐ Antibiotics changes laboratory‐confirmed leptospirosis compared with placebo or no intervention (very low certainty).
1 finding from 1 review
Clinical diagnosis of infection regardless of laboratory confirmed · farmworkers, soldiers, and people in endemic areas
Summary of findings table ‐ Antibiotics showed no clear difference in clinical diagnosis of infection regardless of laboratory confirmed compared with placebo or no intervention (low certainty).
1 finding from 1 review
Clinical diagnosis confirmed by laboratory diagnosis · farmworkers, soldiers, and people in endemic areas
Summary of findings table ‐ Antibiotics showed no clear difference in clinical diagnosis confirmed by laboratory diagnosis compared with placebo or no intervention (low certainty).
1 finding from 1 review
Serious adverse events ‐ not reported · farmworkers, soldiers, and people in endemic areas
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Quality of life ‐ not reported · farmworkers, soldiers, and people in endemic areas
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Non‐serious adverse events · farmworkers, soldiers, and people in endemic areas
It is very uncertain whether summary of findings table ‐ Antibiotics changes non‐serious adverse events compared with placebo or no intervention (very low certainty).
1 finding from 1 review
All‐cause mortality · people with leptospirosis
It is very uncertain whether summary of findings table ‐ Antibiotics changes all‐cause mortality compared with placebo or no intervention (very low certainty).
1 finding from 1 review
Serious adverse event ‐ not reported · people with leptospirosis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events considered non‐serious · people with leptospirosis
It is very uncertain whether summary of findings table ‐ Antibiotics changes adverse events considered non‐serious compared with placebo or no intervention (very low certainty).
1 finding from 1 review
Clinical remission · people with mild‐to‐moderate disease (Rachmilewitz index) or active disease (SCCAI score of 4 to 10)
It is very uncertain whether prebiotics changes clinical remission (14 days) compared with placebo (very low certainty).
1 finding from 1 review
Clinical relapse · people with histologically confirmed diagnosis of ulcerative colitis in remission
Prebiotics showed no clear difference in clinical relapse (6 months) compared with placebo (low certainty).
1 finding from 1 review
Clinical improvement (partial Mayo score) (60 days) · people with histologically confirmed diagnosis of ulcerative colitis in remission
1 finding from 1 review
Health‐related quality of life (timeframe not reported) ‐ IBDQ ‐ Symptoms‐guided diet · people with histologically confirmed diagnosis of ulcerative colitis in remission
1 finding from 1 review
Total adverse events (6 months) · people with histologically confirmed diagnosis of ulcerative colitis in remission
Prebiotics may leads to higher total adverse events (6 months) compared with placebo (low certainty).
1 finding from 1 review
Clinical improvement (Rachmilewitz index) (14 days) · people with mild‐to‐moderate disease (Rachmilewitz index) or active disease (SCCAI score of 4 to 10)
1 finding from 1 review
Withdrawals due to adverse events · people with histologically confirmed diagnosis of ulcerative colitis in remission
It is very uncertain whether prebiotics changes withdrawals due to adverse events (60 days to 6 months) compared with placebo (very low certainty).
1 finding from 1 review
Health‐related quality of life (timeframe not reported) ‐ IBDQ ‐ Symptoms‐guided diet · people with mild‐to‐moderate disease (Rachmilewitz index) or active disease (SCCAI score of 4 to 10)
1 finding from 1 review
no estimate extracted
1 study · 8 participants
Very low
Total adverse events · people with mild‐to‐moderate disease (Rachmilewitz index) or active disease (SCCAI score of 4 to 10)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Withdrawals due to adverse events · people with mild‐to‐moderate disease (Rachmilewitz index) or active disease (SCCAI score of 4 to 10)
It is very uncertain whether prebiotics changes withdrawals due to adverse events (14 days to 2 or 3 months) compared with placebo (very low certainty).
1 finding from 1 review
Infant hospitalisation with laboratory‐confirmed RSV disease · pregnant women
Respiratory syncytial virus vaccine leads to lower infant hospitalisation with laboratory‐confirmed RSV disease compared with placebo (high certainty).
1 finding from 1 review