Rash · rotator cuff disease
Summary of findings: 1.25 mg/day plus rehabilitation showed no clear difference in rash ( compared with placebo plus rehabilitation (low certainty).
1 finding from 1 review
Benefits · rotator cuff disease
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Pain ‐ not reported1 · rotator cuff disease
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Symptom free with activities of daily living (patient rated) ( · rotator cuff disease
Summary of findings: 1.25 mg/day plus rehabilitation showed no clear difference in symptom free with activities of daily living (patient rated) ( compared with placebo plus rehabilitation (low certainty).
1 finding from 1 review
Change in ADAS‐Cog · people with Alzheimer's disease
1 finding from 1 review
Number of participants experiencing any serious adverse events · people with Alzheimer's disease
Vitamin E (capsules 2000 IU/day in two divided doses) showed no clear difference in adverse events Number of participants reporting ≥ 1 serious adverse… compared with placebo (moderate certainty).
1 finding from 1 review
Deaths Number of deaths · people with Alzheimer's disease
Vitamin E (capsules 2000 IU/day in two divided doses) showed no clear difference in deaths Number of deaths compared with placebo (moderate certainty).
1 finding from 1 review
Activities of daily living · people with Alzheimer's disease
1 finding from 1 review
Progression to Alzheimer's disease Number of people progressing to AD · MCI
Vitamin E (capsules 2000 IU/day in two divided doses) showed no clear difference in progression to Alzheimer's disease Number of people progressing to AD compared with placebo (moderate certainty).
1 finding from 1 review
Change in ADAS‐Cog · MCI
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Number of participants experiencing any serious adverse events · MCI
1 finding from 1 review
Death Number of deaths over 36 months · MCI
Vitamin E (capsules 2000 IU/day in two divided doses) showed no clear difference in death Number of deaths over 36 months compared with placebo (moderate certainty).
1 finding from 1 review
Activities of daily living · MCI
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse effects · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
1 finding from 1 review
Patients receiving pentoxifylline reported more adverse events than those in the placebo group but this was not statistically significant (69% reported adverse effects: dizziness, headaches, stomach upset, increased…
1 study · 26 participants
GRADE not reported
Increase in volume of more than 10% compared to the pretreatment measurement · Patients with histologically confirmed CGCG in one or both jaws and normal serum calcium and parathyroid hormone (PTH) levels
Calcitonin (salmon calcitonin nasal spray 200 IU/day) showed no clear difference in increase in volume of more than 10% compared to the pretreatment… compared with placebo; GRADE not reported.
1 finding from 1 review
Adverse events · Patients with histologically confirmed CGCG in one or both jaws and normal serum calcium and parathyroid hormone (PTH) levels
1 finding from 1 review
Adverse events were not described separately for each group. Trialists reported that adverse events were in most patients minimal and consisted of nausea, flushes and some dizziness. One patient had diarrhoea which…
1 study · 14 participants
GRADE not reported
Relief of burning/discomfort (symptom relief; pain intensity) · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
1 finding from 1 review
QoL · people with CAH
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Androgen normalisation · people with CAH
1 finding from 1 review
no estimate extracted
15 participants
Very low
Prevention of adrenal crisis · people with CAH
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found