Findings

What do systematic reviews say?

704 questions · 710 findings · 81 reviews · Headline outcomes only

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No studies found 227 · 32%GRADE not reported 38 · 5.4%Very low 178 · 25.1%Low 178 · 25.1%Moderate 80 · 11.3%High 9 · 1.3%

Cannabidiol vs placebo

CRP (mg/dL) at end of study · people with active UC

1 finding from 1 review

Cannabis for the treatment of ulcerative colitis 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 59 participants
Moderate

Cannabidiol vs placebo

IBDQ at week 6 · people with active UC

1 finding from 1 review

Cannabis for the treatment of ulcerative colitis 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 53 participants
Moderate

Cannabidiol vs placebo

Adverse events · people with active UC

Cannabidiol probably leads to higher adverse events compared with placebo (moderate certainty).

1 finding from 1 review

Cannabis for the treatment of ulcerative colitis 2018 · Cochrane Headline outcomes only
RR 1.28 [1.05, 1.56]
1 study · 60 participants
Moderate

Cannabidiol vs placebo

Serious adverse events · people with active UC

Cannabidiol showed no clear difference in serious adverse events compared with placebo (low certainty).

1 finding from 1 review

Cannabis for the treatment of ulcerative colitis 2018 · Cochrane Headline outcomes only
RR 0.15 [0.01, 2.83]
1 study · 60 participants
Low

Cannabidiol vs placebo

Withdrawals due to adverse events · people with active UC

Cannabidiol showed no clear difference in withdrawal due to adverse event compared with placebo (low certainty).

1 finding from 1 review

Cannabis for the treatment of ulcerative colitis 2018 · Cochrane Headline outcomes only
RR 2.14 [0.83, 5.51]
1 study · 60 participants
Low

Cannabis cigarettes vs placebo

Clinical remission · people with active UC

The review found no eligible studies for this question.

1 finding from 1 review

Cannabis for the treatment of ulcerative colitis 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Cannabis cigarettes vs placebo

Clinical response · people with active UC

The review found no eligible studies for this question.

1 finding from 1 review

Cannabis for the treatment of ulcerative colitis 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Etoricoxib vs placebo

Exacerbation of IBD · IBD patients

Etoricoxib showed no clear difference in exacerbation of IBD compared with placebo (low certainty).

1 finding from 1 review

Tolerability of selective cyclooxygenase 2 inhibitors used for the treatment of rheumatological manifestations of… 2014 · Cochrane Headline outcomes only
RR 0.88 [0.45, 1.69]
1 study · 159 participants
Low

Pelvic floor muscle training vs control

Episodes of urinary incontinence in a 24‐hour period · UUI in women

1 finding from 1 review

Pelvic floor muscle training versus no treatment, or inactive control treatments, for urinary incontinence in women 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 12 participants
Low

Pelvic floor muscle training vs control

Short (up to 1 hour) pad test measured as grams of urine Treatment duration: 6 weeks to 6 months · UUI in women

1 finding from 1 review

Pelvic floor muscle training versus no treatment, or inactive control treatments, for urinary incontinence in women 2018 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Pelvic floor muscle training vs control

GRADE A UI‐specific symptom measures · UUI in women

1 finding from 1 review

Pelvic floor muscle training versus no treatment, or inactive control treatments, for urinary incontinence in women 2018 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Pelvic floor muscle training vs control

GRADE A UI‐specific QoL measures · UUI in women

1 finding from 1 review

Pelvic floor muscle training versus no treatment, or inactive control treatments, for urinary incontinence in women 2018 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Pelvic floor muscle training vs control

Episodes of urinary incontinence in a 24‐hour period · women with SUI

1 finding from 1 review

Pelvic floor muscle training versus no treatment, or inactive control treatments, for urinary incontinence in women 2018 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 432 participants
Moderate

Pelvic floor muscle training vs control

Episodes of urinary incontinence in a 24‐hour period · women with UI (all types)

1 finding from 1 review

Pelvic floor muscle training versus no treatment, or inactive control treatments, for urinary incontinence in women 2018 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 349 participants
Moderate

Manipulation (cervical) vs oral medicine

Pain · patients with acute and subacute neck pain

The review found no eligible studies for this question.

1 finding from 1 review

Manipulation and mobilisation for neck pain contrasted against an inactive control or another active treatment 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Manipulation vs mobilisation

Pain · patients with acute, subacute and chronic neck pain

The review found no eligible studies for this question.

1 finding from 1 review

Manipulation and mobilisation for neck pain contrasted against an inactive control or another active treatment 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Manipulation vs mobilisation

Acute, subacute and chronic neck pain Intermediate‐term · patients with acute, subacute and chronic neck pain

Manipulation showed no clear difference in acute, subacute and chronic neck pain Intermediate‐term compared with mobilisation (moderate certainty).

1 finding from 1 review

Manipulation and mobilisation for neck pain contrasted against an inactive control or another active treatment 2015 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 446 participants
Moderate

Manipulation vs mobilisation

FUNCTION AND DISABILITY · patients with acute, subacute and chronic neck pain

The review found no eligible studies for this question.

1 finding from 1 review

Manipulation and mobilisation for neck pain contrasted against an inactive control or another active treatment 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Manipulation vs mobilisation

Acute and subacute neck pain Short‐term · patients with acute, subacute and chronic neck pain

Manipulation showed no clear difference in acute and subacute neck pain Short‐term compared with mobilisation (moderate certainty).

1 finding from 1 review

Manipulation and mobilisation for neck pain contrasted against an inactive control or another active treatment 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 176 participants
Moderate

Manipulation vs mobilisation

Participant satisfaction · patients with acute, subacute and chronic neck pain

The review found no eligible studies for this question.

1 finding from 1 review

Manipulation and mobilisation for neck pain contrasted against an inactive control or another active treatment 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found