Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,678 questions · 4,859 findings · 283 reviews

No studies found 1,225 · 25.2%GRADE not reported 215 · 4.4%Very low 1,241 · 25.5%Low 1,210 · 24.9%Moderate 776 · 16%High 192 · 4%

HALOPERIDOL vs lorazepam

Adverse events including extrapyramidal effects · terminally ill adults with delirium

It is very uncertain whether summary of findings: haloperidol changes adverse events including extrapyramidal effectsc compared with lorazepam (very low certainty).

1 finding from 1 review

HALOPERIDOL vs placebo

Adverse events including extrapyramidal effects · terminally ill adults with delirium

Summary of findings: haloperidol showed no clear difference in adverse events including extrapyramidal effectse compared with placebo (moderate certainty).

1 finding from 1 review

HALOPERIDOL vs RISPERIDONE

Symptoms of delirium within 24 hoursa · terminally ill adults with delirium

Summary of findings: haloperidol showed no clear difference in symptoms of delirium within 24 hoursa compared with risperidone (low certainty).

1 finding from 1 review

HALOPERIDOL vs RISPERIDONE

Symptoms of delirium between 24 and 48 hoursa · terminally ill adults with delirium

Summary of findings: haloperidol showed no clear difference in symptoms of delirium between 24 and 48 hoursa compared with risperidone (low certainty).

1 finding from 1 review

Summary of findings: bevacizumab vs ranibizumab

Mean change in visual acuity at 1 year (number of letters) · people with neovascular age‐related macular degeneration

Summary of findings: bevacizumab showed no clear difference in mean change in visual acuity at 1 year (number of letters) compared with ranibizumab (high certainty).

1 finding from 1 review

Summary of findings: bevacizumab vs ranibizumab

Reduction in central retinal thickness at one year · people with neovascular age‐related macular degeneration

Summary of findings: bevacizumab showed no clear difference in reduction in central retinal thickness at 1 year compared with ranibizumab (high certainty).

1 finding from 1 review

Summary of findings: bevacizumab vs ranibizumab

No problems in quality of life domains at one year · people with neovascular age‐related macular degeneration

Summary of findings: bevacizumab showed no clear difference in no problems in quality of life domains at 1 year compared with ranibizumab (moderate certainty).

1 finding from 1 review

Summary of findings: bevacizumab vs ranibizumab

Serious systemic adverse events at one year · people with neovascular age‐related macular degeneration

Summary of findings: bevacizumab showed no clear difference in serious systemic adverse events at 1 yearb compared with ranibizumab (moderate certainty).

1 finding from 1 review

Summary of findings: bevacizumab vs ranibizumab

BCVA: gain of 15 or more ETDRS letters · people with neovascular age‐related macular degeneration

Summary of findings: bevacizumab showed no clear difference in gain of 15 or more letters visual acuity at 1 year compared with ranibizumab (high certainty).

1 finding from 1 review

Summary of findings: bevacizumab vs ranibizumab

Loss of fewer than 15 letters visual acuity at one year · people with neovascular age‐related macular degeneration

Summary of findings: bevacizumab showed no clear difference in loss of fewer than 15 letters visual acuity at 1 year compared with ranibizumab (high certainty).

1 finding from 1 review