Question · asked by 1 review

Summary of findings: bevacizumab vs ranibizumab: Loss of fewer than 15 letters visual acuity at one year

Summary of findings: bevacizumab showed no clear difference in loss of fewer than 15 letters visual acuity at 1 year compared with ranibizumab (high certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Summary of findings: bevacizumab vs ranibizumab
Loss of fewer than 15 letters visual acuity at 1 year · people with neovascular age‐related macular degeneration
Summary of findings: bevacizumab showed no clear difference in loss of fewer than 15 letters visual acuity at 1 year compared with ranibizumab (high certainty).
Anti‐vascular endothelial growth factor for neovascular age‐related macular degeneration (2019) · Cochrane Headline outcomes only
RR 1 [0.98, 1.02]8 studies · 3144 participantsHigh

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Anti‐vascular endothelial growth factor for neovascular age‐related macular degeneration
2019 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.