Question · asked by 1 review

HALOPERIDOL vs lorazepam: Adverse events including extrapyramidal effects

Population
terminally ill adults with delirium
Intervention
HALOPERIDOL
Comparison
lorazepam
Outcome
Adverse events including extrapyramidal effects

It is very uncertain whether summary of findings: haloperidol changes adverse events including extrapyramidal effectsc compared with lorazepam (very low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Summary of findings: haloperidol vs lorazepam
Adverse events including extrapyramidal effectsc · terminally ill adults with delirium
It is very uncertain whether summary of findings: haloperidol changes adverse events including extrapyramidal effectsc compared with lorazepam (very low certainty).
Drug therapy for delirium in terminally ill adults (2020) · Cochrane Headline outcomes only
no estimate extracted1 study · 16 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Drug therapy for delirium in terminally ill adults
2020 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed

The same intervention and outcome, asked in another population or against another comparator.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.