HALOPERIDOL vs placebo: Adverse events including extrapyramidal effects
- Population
- terminally ill adults with delirium
- Intervention
- HALOPERIDOL
- Comparison
- placebo
- Outcome
- Adverse events including extrapyramidal effects
Summary of findings: haloperidol showed no clear difference in adverse events including extrapyramidal effectse compared with placebo (moderate certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Summary of findings: haloperidol vs placebo Adverse events including extrapyramidal effectse · terminally ill adults with delirium Summary of findings: haloperidol showed no clear difference in adverse events including extrapyramidal effectse compared with placebo (moderate certainty). Drug therapy for delirium in terminally ill adults (2020) · Cochrane Headline outcomes only | MD 0.79 | 1 study · 123 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Drug therapy for delirium in terminally ill adults 2020 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- HALOPERIDOL vs lorazepam · terminally ill adults with delirium · 1 review
- HALOPERIDOL vs RISPERIDONE · terminally ill adults with delirium · 1 review
- HALOPERIDOL vs chlorpromazine · terminally ill adults with delirium · 1 review
- HALOPERIDOL vs OLANZAPINE · terminally ill adults with delirium · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.