Findings

What do systematic reviews say?

3,971 questions · 9,849 findings · 853 reviews

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No studies found 1,150 · 11.7%GRADE not reported 3,387 · 34.4%Very low 1,963 · 19.9%Low 1,809 · 18.4%Moderate 1,207 · 12.3%High 333 · 3.4%

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Avalglucosidase alfa vs alglucosidase alfa

Change from baseline in 6MWT (metres) · adults with LOPD

1 finding from 1 review

Enzyme replacement therapy for late‐onset Pompe disease 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 100 participants
Moderate

Alglucosidase alfa plus clenbuterol vs alglucosidase alfa plus placebo

Change from baseline in 6MWT (metres) · 13 people with LOPD

1 finding from 1 review

Enzyme replacement therapy for late‐onset Pompe disease 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 10 participants
Very low

Intervention not reported

Finding 13. Healthcare providers and policymakers highlighted the need for adequate equipment, infrastructure and maintenance both on the provider side and the patient side but described how these needs were not always met. They described challeng...

1 finding from 1 review

Factors that influence the provision of home‐based rehabilitation services for people needing rehabilitation: a… 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Moderate

Phacoemulsification vs laser peripheral iridotomy

Mean IOP ( · Participants with acute primary angle closure after initial medical treatment to lower intraocular pressure

1 finding from 1 review

Lens extraction versus laser peripheral iridotomy for acute primary angle closure 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 62 participants
Low

Phacoemulsification vs laser peripheral iridotomy

Mean change in angle findings, measured by any method · Participants with acute primary angle closure after initial medical treatment to lower intraocular pressure

1 finding from 1 review

Lens extraction versus laser peripheral iridotomy for acute primary angle closure 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 94 participants
Very low

Local corticosteroid injection (LCI) vs saline no treatment or placebo

Improvement in neurophysiological parameters at ≤ 3 months · carpal tunnel syndrome

1 finding from 1 review

Local corticosteroid injection versus placebo for carpal tunnel syndrome 2023 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 359 participants
Very low

Intervention not reported

Anthropometric recovery: percentage of children who recover from moderate or severe wasting Defined as % children aged 6–59 months who recovered in treatment programmes for moderate or severe malnutrition (Wroe 2021) · children aged > 6 months and ≤ 5 years with wasting

1 finding from 1 review

Lay health workers in primary and community health care for maternal and child health: identification and treatment of… 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 90 participants
Low

Intervention not reported

Anthropometric recovery: improvement from severe wasting Defined as MUAC ≥ 115 mm, clinically well, absence of oedema for 2 consecutive visits, and minimum stay of 8 weeks in the programme (Hussain 2021) · children aged > 6 months and ≤ 5 years with wasting

The intervention may leads to lower anthropometric recovery: improvement from severe wasting Defined as… (low certainty).

1 finding from 1 review

Lay health workers in primary and community health care for maternal and child health: identification and treatment of… 2023 · Cochrane Headline outcomes only
RR 0.93 [0.86, 0.99]
1 study · 789 participants
Low

Intervention not reported

Anthropometric recovery Defined as: WHZ ≥ −1.5 or MUAC > 125 mm for 2 consecutive visits and absence of nutritional oedema for 14 days (Alvarez Moran 2018b); absence of oedema and WHZ ≥ −1.5 or MUAC > 125 mm (Charle‐Cuellar 2021c; no oedema and we... · children aged > 6 months and < 5 years with wasting

It is very uncertain whether the intervention changes anthropometric recovery Defined as: WHZ ≥ −1.5 or MUAC > 125 mm for… (very low certainty).

1 finding from 1 review

Lay health workers in primary and community health care for maternal and child health: identification and treatment of… 2023 · Cochrane Headline outcomes only
RR 1.06 [1, 1.11]
5 studies · 6688 participants
Very low

Intervention not reported

Anthropometric outcomes: total MUAC gain Defined as MUAC at discharge − MUAC on admission among children with no oedema and discharged as cured (Charle‐Cuellar 2021)c · children aged > 6 months and < 5 years with wasting

1 finding from 1 review

Lay health workers in primary and community health care for maternal and child health: identification and treatment of… 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 532 participants
Very low

Intervention not reported

Anthropometric outcomes: MUAC gain per day Defined as (discharge MUAC − admission MUAC)/days in treatment among children with no oedema and discharged as cured (Charle‐Cuellar 2021)c · children aged > 6 months and < 5 years with wasting

1 finding from 1 review

Lay health workers in primary and community health care for maternal and child health: identification and treatment of… 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 531 participants
Very low

Intervention not reported

Anthropometric outcomes: total weight gain (g/kg) Defined as (weight at discharge − weight on admission)/weight on admission among children with no oedema and discharged as cured (Charle‐Cuellar 2021)c · children aged > 6 months and < 5 years with wasting

1 finding from 1 review

Lay health workers in primary and community health care for maternal and child health: identification and treatment of… 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 517 participants
Very low

Intervention not reported

Anthropometric outcomes: mean weight gain per day (g/kg/d) Defined as ((discharge weight − admission weight)/admission weight)/days in treatment (Wilunda 2021)e · children aged > 6 months and < 5 years with wasting

1 finding from 1 review

Lay health workers in primary and community health care for maternal and child health: identification and treatment of… 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 343 participants
Very low

Intervention not reported

Anthropometric outcomes: median weight gain per day (g/kg/d) Defined as ((discharge weight − admission weight)/weight on admission)/days on treatment among children with no oedema and discharged as cured (Charle‐Cuellar 2021)c · children aged > 6 months and < 5 years with wasting

1 finding from 1 review

Lay health workers in primary and community health care for maternal and child health: identification and treatment of… 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 517 participants
Very low

Intervention not reported

Anthropometric outcomes: number of children with normal or underweight WHZ on discharge Defined as WHZ > −2 (Hussain 2021) · children aged > 6 months and ≤ 5 years with wasting

The intervention showed no clear difference in anthropometric outcomes: number of children with normal or… (low certainty).

1 finding from 1 review

Lay health workers in primary and community health care for maternal and child health: identification and treatment of… 2023 · Cochrane Headline outcomes only
RR 0.94 [0.28, 3.18]
1 study · 789 participants
Low

Intervention not reported

Anthropometric outcomes: number of children with WHZ in moderate wasting range on discharge Defined as WHZ between −3 and −2 (Hussain 2021) · children aged > 6 months and ≤ 5 years with wasting

The intervention showed no clear difference in anthropometric outcomes: number of children with WHZ in moderate… (moderate certainty).

1 finding from 1 review

Lay health workers in primary and community health care for maternal and child health: identification and treatment of… 2023 · Cochrane Headline outcomes only
RR 1.09 [0.87, 1.36]
1 study · 789 participants
Moderate

Intervention not reported

Anthropometric outcomes: number of children with WHZ in severe wasting range on discharge Defined as WHZ < −3: Hussain 2021 · children aged > 6 months and ≤ 5 years with wasting

The intervention showed no clear difference in anthropometric outcomes: number of children with WHZ in severe… (moderate certainty).

1 finding from 1 review

Lay health workers in primary and community health care for maternal and child health: identification and treatment of… 2023 · Cochrane Headline outcomes only
RR 1.23 [0.75, 2.04]
1 study · 789 participants
Moderate

Intervention not reported

Anthropometric outcomes: number of children with MUAC ≥ 115 mm on discharge (Hussain 2021) · children aged > 6 months and ≤ 5 years with wasting

The intervention showed no clear difference in anthropometric outcomes: number of children with MUAC ≥ 115 mm on… (moderate certainty).

1 finding from 1 review

Lay health workers in primary and community health care for maternal and child health: identification and treatment of… 2023 · Cochrane Headline outcomes only
RR 0.99 [0.93, 1.06]
1 study · 789 participants
Moderate

Intervention not reported

Anthropometric outcomes: weight gain per day (g/kg/day) Calculated as ((discharge weight − admission weight)/weight on admission)/days in treatment among recovered children (Hussain 2021) · children aged > 6 months and ≤ 5 years with wasting

1 finding from 1 review

Lay health workers in primary and community health care for maternal and child health: identification and treatment of… 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 571 participants
High

Intervention not reported

Potency/bioactivity parameters of human insulin · healthy physicians

The review found no eligible studies for this question.

1 finding from 1 review

Thermal stability and storage of human insulin 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found