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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Population

Intervention or exposure

Comparison

Outcome

Any field or review title

Field or topic

Source

Review versions

1,645 questions in 107 reviews · Wounds

current versions

No studies 651 · 39.6%Ungraded 84 · 5.1%Very low 554 · 33.7%Low 283 · 17.2%Moderate 64 · 3.9%High 9 · 0.5%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Question	Effect	Evidence	Status / GRADE
Dextranomer beads (autolytic) vs Eusol gauze Time to complete healing (days) · adults with surgical wounds Debridement for surgical wounds (2024) · Cochrane	no estimate extracted	NR	No studies
Dextranomer beads (autolytic) vs Eusol gauze Serious adverse events: life‐threatening/ hospitalisation · adults with surgical wounds Debridement for surgical wounds (2024) · Cochrane	no estimate extracted	NR	No studies
Dextranomer paste (autolytic) vs 10% aqueous polyvinylpyrrolidone Time to a clean wound bed ( · adults with surgical wounds Debridement for surgical wounds (2024) · Cochrane	no estimate extracted	1 study · 40 participants	Very low
Dextranomer paste (autolytic) vs 10% aqueous polyvinylpyrrolidone Proportion of wounds completely debrided · adults with surgical wounds Debridement for surgical wounds (2024) · Cochrane	no estimate extracted	NR	No studies
Dextranomer paste (autolytic) vs 10% aqueous polyvinylpyrrolidone Rate of reduction in wound size · adults with surgical wounds Debridement for surgical wounds (2024) · Cochrane	no estimate extracted	NR	No studies
Standard polyurethane plus tissue adhesive vs standard polyurethane Arterial catheter failure assessed during catheter dwell · people with arterial catheter dressing and securement Dressings and securement devices to prevent complications for peripheral arterial catheters (2024) · Cochrane	RR 0.44 [0.2, 0.98]	2 studies · 165 participants	Very low
Bordered polyurethane vs standard polyurethane Adverse events assessed during catheter dwell · people with arterial catheter dressing and securement Dressings and securement devices to prevent complications for peripheral arterial catheters (2024) · Cochrane	RR 0.33 [0.01, 7.87]	1 study · 60 participants	Very low
Standard polyurethane plus sutureless securement devices vs standard polyurethane Arterial catheter failureassessed during catheter dwell · people with arterial catheter dressing and securement Dressings and securement devices to prevent complications for peripheral arterial catheters (2024) · Cochrane	RR 0.78 [0.4, 1.52]	2 studies · 157 participants	Very low
Standard polyurethane plus sutureless securement devices vs standard polyurethane Incidence of catheter‐related bloodstream infection assessed during catheter dwell or 48 hours after removal · people with arterial catheter dressing and securement Dressings and securement devices to prevent complications for peripheral arterial catheters (2024) · Cochrane	no estimate extracted	2 studies · 157 participants	Very low
Standard polyurethane plus sutureless securement devices vs standard polyurethane Dislodgement assessed during catheter dwell · people with arterial catheter dressing and securement Dressings and securement devices to prevent complications for peripheral arterial catheters (2024) · Cochrane	RR 0.14 [0.01, 2.57]	2 studies · 157 participants	Very low
Standard polyurethane plus sutureless securement devices vs standard polyurethane Occlusion assessed during catheter dwell · people with arterial catheter dressing and securement Dressings and securement devices to prevent complications for peripheral arterial catheters (2024) · Cochrane	RR 1.94 [0.5, 7.48]	2 studies · 157 participants	Very low
Standard polyurethane plus sutureless securement devices vs standard polyurethane Adverse events assessed during catheter dwell and on product removal · people with arterial catheter dressing and securement Dressings and securement devices to prevent complications for peripheral arterial catheters (2024) · Cochrane	RR 1.94 [0.19, 20.24]	2 studies · 157 participants	Very low
Integrated securement dressings vs standard polyurethane Arterial catheter failureassessed during catheter dwell or 48 hours after removal · people with arterial catheter dressing and securement Dressings and securement devices to prevent complications for peripheral arterial catheters (2024) · Cochrane	RR 1.96 [0.8, 4.84]	1 study · 105 participants	Low
Integrated securement dressings vs standard polyurethane Incidence of catheter‐related bloodstream infectionassessed during catheter dwell or 48 hours after removal · people with arterial catheter dressing and securement Dressings and securement devices to prevent complications for peripheral arterial catheters (2024) · Cochrane	no estimate extracted	1 study · 105 participants	Low
Integrated securement dressings vs standard polyurethane Dislodgement assessed during catheter dwell · people with arterial catheter dressing and securement Dressings and securement devices to prevent complications for peripheral arterial catheters (2024) · Cochrane	RR 0.33 [0.04, 3.04]	1 study · 105 participants	Low
Integrated securement dressings vs standard polyurethane Occlusion assessed during catheter dwell · people with arterial catheter dressing and securement Dressings and securement devices to prevent complications for peripheral arterial catheters (2024) · Cochrane	no estimate extracted	1 study · 105 participants	Low
Standard polyurethane plus tissue adhesive vs standard polyurethane Incidence of catheter‐related bloodstream infection assessed during catheter dwell or 48 hours after removal · people with arterial catheter dressing and securement Dressings and securement devices to prevent complications for peripheral arterial catheters (2024) · Cochrane	no estimate extracted	2 studies · 165 participants	Very low
Integrated securement dressings vs standard polyurethane Adverse events assessed during catheter dwell or on product removal · people with arterial catheter dressing and securement Dressings and securement devices to prevent complications for peripheral arterial catheters (2024) · Cochrane	RR 0.35 [0.01, 8.45]	1 study · 105 participants	Low
Standard polyurethane plus tissue adhesive vs standard polyurethane Dislodgement assessed during catheter dwell · people with arterial catheter dressing and securement Dressings and securement devices to prevent complications for peripheral arterial catheters (2024) · Cochrane	RR 0.54 [0.03, 9.62]	2 studies · 165 participants	Very low
Standard polyurethane plus tissue adhesive vs standard polyurethane Occlusion assessed during catheter dwell · people with arterial catheter dressing and securement Dressings and securement devices to prevent complications for peripheral arterial catheters (2024) · Cochrane	RR 1.2 [0.37, 3.91]	2 studies · 165 participants	Very low
Standard polyurethane plus tissue adhesive vs standard polyurethane Adverse events assessed during catheter dwell and on product removal · people with arterial catheter dressing and securement Dressings and securement devices to prevent complications for peripheral arterial catheters (2024) · Cochrane	RR 0.89 [0.09, 8.33]	2 studies · 165 participants	Very low
Bordered polyurethane vs standard polyurethane Arterial catheter failureassessed during catheter dwell · people with arterial catheter dressing and securement Dressings and securement devices to prevent complications for peripheral arterial catheters (2024) · Cochrane	RR 0.67 [0.21, 2.13]	1 study · 60 participants	Very low
Bordered polyurethane vs standard polyurethane Incidence of catheter‐related bloodstream infectionassessed during catheter dwell or 48 hours after removal · people with arterial catheter dressing and securement Dressings and securement devices to prevent complications for peripheral arterial catheters (2024) · Cochrane	RR 3.05 [0.12, 74.45]	2 studies · 572 participants	Low
Bordered polyurethane vs standard polyurethane Dislodgement assessed during catheter dwell · people with arterial catheter dressing and securement Dressings and securement devices to prevent complications for peripheral arterial catheters (2024) · Cochrane	RR 0.75 [0.17, 3.22]	2 studies · 572 participants	Low
Bordered polyurethane vs standard polyurethane Occlusion assessed during catheter dwell · people with arterial catheter dressing and securement Dressings and securement devices to prevent complications for peripheral arterial catheters (2024) · Cochrane	RR 0.8 [0.6, 1.07]	2 studies · 572 participants	Low
Doxepin cream vs oral antihistamine Change in burn‐related pruritus (VAS) ( · people with postburn pruritus Interventions for postburn pruritus (2024) · Cochrane	no estimate extracted	2 studies · 49 participants	Low
Ondansetron vs diphenhydramine (antihistamine) Change in burn‐related pruritus (NAS) ( · people with postburn pruritus Interventions for postburn pruritus (2024) · Cochrane	no estimate extracted	1 study · 38 participants	Moderate
Ondansetron vs diphenhydramine (antihistamine) Adverse events · people with postburn pruritus Interventions for postburn pruritus (2024) · Cochrane	no estimate extracted	NR	No studies
Ondansetron vs diphenhydramine (antihistamine) Pain · people with postburn pruritus Interventions for postburn pruritus (2024) · Cochrane	no estimate extracted	NR	No studies
Enalapril ointment vs placebo Change in burn‐related pruritus (Scoring table for itching) ( · people with postburn pruritus Interventions for postburn pruritus (2024) · Cochrane	no estimate extracted	1 study · 60 participants	Moderate
Enalapril ointment vs placebo Adverse events · people with postburn pruritus Interventions for postburn pruritus (2024) · Cochrane	no estimate extracted	NR	No studies
Enalapril ointment vs placebo Pain · people with postburn pruritus Interventions for postburn pruritus (2024) · Cochrane	no estimate extracted	NR	No studies
Massage therapy vs standard care Change in burn‐related pruritus Itching scale ( · people with postburn pruritus Interventions for postburn pruritus (2024) · Cochrane	no estimate extracted	2 studies · 166 participants	Low
Massage therapy vs standard care Adverse events · people with postburn pruritus Interventions for postburn pruritus (2024) · Cochrane	no estimate extracted	NR	No studies
Massage therapy vs standard care Pain VAS for pain ( · people with postburn pruritus Interventions for postburn pruritus (2024) · Cochrane	no estimate extracted	2 studies · 166 participants	Low
Extracorporeal shock wave therapy vs sham Change in burn‐related pruritus NRS ( · people with postburn pruritus Interventions for postburn pruritus (2024) · Cochrane	no estimate extracted	2 studies · 91 participants	Low
Doxepin cream vs oral antihistamine Adverse events (somnolence) · people with postburn pruritus Interventions for postburn pruritus (2024) · Cochrane	RR 0.64 [0.32, 1.25]	1 study · 24 participants	Very low
Extracorporeal shock wave therapy vs sham Adverse events · people with postburn pruritus Interventions for postburn pruritus (2024) · Cochrane	no estimate extracted	NR	No studies
Extracorporeal shock wave therapy vs sham Pain Pressure pain threshold (PPT) ( · people with postburn pruritus Interventions for postburn pruritus (2024) · Cochrane	MD 2.96 [1.76, 4.16]	1 study · 45 participants	Low
Pulsed high‐intensity laser vs placebo laser Change in burn‐related pruritus Itch Severity Scale (ISS) ( · people with postburn pruritus Interventions for postburn pruritus (2024) · Cochrane	no estimate extracted	1 study · 49 participants	Moderate
Pulsed high‐intensity laser vs placebo laser Adverse events · people with postburn pruritus Interventions for postburn pruritus (2024) · Cochrane	no estimate extracted	NR	No studies
Pulsed high‐intensity laser vs placebo laser Pain VAS ( · people with postburn pruritus Interventions for postburn pruritus (2024) · Cochrane	no estimate extracted	1 study · 49 participants	Moderate
Doxepin cream vs oral antihistamine Pain · people with postburn pruritus Interventions for postburn pruritus (2024) · Cochrane	no estimate extracted	NR	No studies
Gabapentin vs cetirizine (antihistamine) Change in burn‐related pruritus (VAS) ( · people with postburn pruritus Interventions for postburn pruritus (2024) · Cochrane	no estimate extracted	1 study · 40 participants	Low
Gabapentin vs cetirizine (antihistamine) Adverse events (somnolence) · people with postburn pruritus Interventions for postburn pruritus (2024) · Cochrane	RR 0.02 [0, 0.38]	1 study · 40 participants	Low
Gabapentin vs cetirizine (antihistamine) Pain · people with postburn pruritus Interventions for postburn pruritus (2024) · Cochrane	no estimate extracted	NR	No studies
Pregabalin vs cetirizine with pheniramine maleate (antihistamine) Change in burn‐related pruritus (VAS) ( · people with postburn pruritus Interventions for postburn pruritus (2024) · Cochrane	no estimate extracted	1 study · 40 participants	Low
Pregabalin vs cetirizine with pheniramine maleate (antihistamine) Adverse events (drowsiness) · people with postburn pruritus Interventions for postburn pruritus (2024) · Cochrane	RR 0.04 [0, 0.69]	1 study · 40 participants	Low
Pregabalin vs cetirizine with pheniramine maleate (antihistamine) Pain · people with postburn pruritus Interventions for postburn pruritus (2024) · Cochrane	no estimate extracted	NR	No studies
Pressure‐garment therapy (PGT) vs no treatment/lanolin Scar improvement (VSS) (0–13, higher score = more severe scarring) · people with burn wounds likely to develop hypertrophic scarring Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane	no estimate extracted	3 studies · 187 participants	Very low