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Search review questions
Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
1,248 questions in 108 reviews · Stroke
current versionsNo studies 275 · 22%Ungraded 56 · 4.5%Very low 269 · 21.6%Low 349 · 28%Moderate 216 · 17.3%High 83 · 6.7%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Endovascular therapy plus conventional medical treatment vs conventional medical treatment alone Dependency · people with symptomatic intracranial artery stenosis Endovascular therapy versus medical treatment for symptomatic intracranial artery stenosis (2023) · Cochrane | RR 1.51 [0.93, 2.45] | 4 studies · 947 participants | Moderate |
Endovascular therapy plus conventional medical treatment vs conventional medical treatment alone Restenosis (≥ 50%) · people with symptomatic intracranial artery stenosis Endovascular therapy versus medical treatment for symptomatic intracranial artery stenosis (2023) · Cochrane | no estimate extracted | NR | No studies |
Endovascular therapy plus conventional medical treatment vs conventional medical treatment alone Health‐related quality of life · people with symptomatic intracranial artery stenosis Endovascular therapy versus medical treatment for symptomatic intracranial artery stenosis (2023) · Cochrane | no estimate extracted | NR | No studies |
Antiplatelet agent vs placebo Outcomes (measurement) · asymptomatic carotid stenosis Pharmacological interventions for asymptomatic carotid stenosis (2023) · Cochrane | no estimate extracted | NR | No studies |
Antihypertensive agent vs placebo Neurological impairment · asymptomatic carotid stenosis Pharmacological interventions for asymptomatic carotid stenosis (2023) · Cochrane | no estimate extracted | NR | No studies |
Antihypertensive agent vs placebo Ipsilateral major or disabling stroke (not reported) · asymptomatic carotid stenosis Pharmacological interventions for asymptomatic carotid stenosis (2023) · Cochrane | RR 0.14 [0.02, 1.16] | 1 study · 793 participants | Low |
Antihypertensive agent vs placebo Stroke‐related mortality (not reported) · asymptomatic carotid stenosis Pharmacological interventions for asymptomatic carotid stenosis (2023) · Cochrane | RR 0.57 [0.17, 1.94] | 1 study · 793 participants | Low |
Antihypertensive agent vs placebo Major bleeding · asymptomatic carotid stenosis Pharmacological interventions for asymptomatic carotid stenosis (2023) · Cochrane | no estimate extracted | NR | No studies |
Antihypertensive agent vs placebo Progression of carotid stenosis (DUS/at beginning and end) · asymptomatic carotid stenosis Pharmacological interventions for asymptomatic carotid stenosis (2023) · Cochrane | RR 0.45 [0.23, 0.91] | 1 study · 129 participants | Low |
Antihypertensive agent vs placebo Adverse events · asymptomatic carotid stenosis Pharmacological interventions for asymptomatic carotid stenosis (2023) · Cochrane | no estimate extracted | NR | No studies |
Antihypertensive agent vs placebo Quality of life · asymptomatic carotid stenosis Pharmacological interventions for asymptomatic carotid stenosis (2023) · Cochrane | no estimate extracted | NR | No studies |
Anticoagulant agent vs placebo Outcomes (measurement/time point) · asymptomatic carotid stenosis Pharmacological interventions for asymptomatic carotid stenosis (2023) · Cochrane | no estimate extracted | NR | No studies |
Anticoagulant agent vs placebo Neurological impairment · asymptomatic carotid stenosis Pharmacological interventions for asymptomatic carotid stenosis (2023) · Cochrane | no estimate extracted | NR | No studies |
Anticoagulant agent vs placebo Ipsilateral major or disabling stroke · asymptomatic carotid stenosis Pharmacological interventions for asymptomatic carotid stenosis (2023) · Cochrane | no estimate extracted | NR | No studies |
Antiplatelet agent vs placebo Neurological impairment · asymptomatic carotid stenosis Pharmacological interventions for asymptomatic carotid stenosis (2023) · Cochrane | no estimate extracted | NR | No studies |
Anticoagulant agent vs placebo Stroke‐related mortality · asymptomatic carotid stenosis Pharmacological interventions for asymptomatic carotid stenosis (2023) · Cochrane | no estimate extracted | NR | No studies |
Anticoagulant agent vs placebo Major bleeding (hospital records/every 6 weeks) · asymptomatic carotid stenosis Pharmacological interventions for asymptomatic carotid stenosis (2023) · Cochrane | RR 1.19 [0.97, 1.46] | 1 study · 919 participants | Very low |
Anticoagulant agent vs placebo Progression of carotid stenosis · asymptomatic carotid stenosis Pharmacological interventions for asymptomatic carotid stenosis (2023) · Cochrane | no estimate extracted | NR | No studies |
Anticoagulant agent vs placebo Adverse events (hospital records/every 6 weeks) · asymptomatic carotid stenosis Pharmacological interventions for asymptomatic carotid stenosis (2023) · Cochrane | RR 0.89 [0.81, 0.99] | 1 study · 919 participants | Low |
Anticoagulant agent vs placebo Quality of life · asymptomatic carotid stenosis Pharmacological interventions for asymptomatic carotid stenosis (2023) · Cochrane | no estimate extracted | NR | No studies |
Lipid‐lowering agent vs placebo or no treatment Outcomes (measurement/time point) · asymptomatic carotid stenosis Pharmacological interventions for asymptomatic carotid stenosis (2023) · Cochrane | no estimate extracted | NR | No studies |
Lipid‐lowering agent vs placebo or no treatment Neurological impairment · asymptomatic carotid stenosis Pharmacological interventions for asymptomatic carotid stenosis (2023) · Cochrane | no estimate extracted | NR | No studies |
Lipid‐lowering agent vs placebo or no treatment Ipsilateral major or disabling stroke (only reported for two studies: one used CT scan, MRI and hospital records/every 6 weeksb; the other used physical examination/at beginning and 10 days after the endc) · asymptomatic carotid stenosis Pharmacological interventions for asymptomatic carotid stenosis (2023) · Cochrane | RR 0.36 [0.09, 1.53] | 5 studies · 2235 participants | Low |
Lipid‐lowering agent vs placebo or no treatment Stroke‐related mortality (only reported for one study: CT scan, MRI and hospital records/every 6 weeksb) · asymptomatic carotid stenosis Pharmacological interventions for asymptomatic carotid stenosis (2023) · Cochrane | RR 0.25 [0.03, 2.29] | 2 studies · 1366 participants | Low |
Lipid‐lowering agent vs placebo or no treatment Major bleeding · asymptomatic carotid stenosis Pharmacological interventions for asymptomatic carotid stenosis (2023) · Cochrane | no estimate extracted | NR | No studies |
Antiplatelet agent vs placebo Ipsilateral major or disabling stroke (CT scan or MRI) · asymptomatic carotid stenosis Pharmacological interventions for asymptomatic carotid stenosis (2023) · Cochrane | RR 1.08 [0.47, 2.47] | 1 study · 372 participants | Low |
Lipid‐lowering agent vs placebo or no treatment Progression of carotid stenosis · asymptomatic carotid stenosis Pharmacological interventions for asymptomatic carotid stenosis (2023) · Cochrane | no estimate extracted | NR | No studies |
Lipid‐lowering agent vs placebo or no treatment Adverse events (only reported for two studies: one study used CT scan, MRI and hospital records/every 6 weeksb; the other used physical examination/at beginning and 10 days after the endc) · asymptomatic carotid stenosis Pharmacological interventions for asymptomatic carotid stenosis (2023) · Cochrane | RR 0.76 [0.53, 1.1] | 7 studies · 3726 participants | Low |
Lipid‐lowering agent vs placebo or no treatment Quality of life · asymptomatic carotid stenosis Pharmacological interventions for asymptomatic carotid stenosis (2023) · Cochrane | no estimate extracted | NR | No studies |
Antiplatelet agent vs placebo Stroke‐related mortality (CT scan or MRI) · asymptomatic carotid stenosis Pharmacological interventions for asymptomatic carotid stenosis (2023) · Cochrane | RR 1.4 [0.54, 3.59] | 1 study · 372 participants | Low |
Antiplatelet agent vs placebo Major bleeding (not reported) · asymptomatic carotid stenosis Pharmacological interventions for asymptomatic carotid stenosis (2023) · Cochrane | RR 0.98 [0.06, 15.53] | 1 study · 372 participants | Very low |
Antiplatelet agent vs placebo Progression of carotid stenosis (DUS/every 6 months) · asymptomatic carotid stenosis Pharmacological interventions for asymptomatic carotid stenosis (2023) · Cochrane | RR 1.16 [0.79, 1.71] | 1 study · 372 participants | Low |
Antiplatelet agent vs placebo Adverse events (not reported) · asymptomatic carotid stenosis Pharmacological interventions for asymptomatic carotid stenosis (2023) · Cochrane | RR 0.81 [0.41, 1.59] | 1 study · 372 participants | Low |
Antiplatelet agent vs placebo Quality of life · asymptomatic carotid stenosis Pharmacological interventions for asymptomatic carotid stenosis (2023) · Cochrane | no estimate extracted | NR | No studies |
Antihypertensive agent vs placebo Outcomes (measurement/time point) · asymptomatic carotid stenosis Pharmacological interventions for asymptomatic carotid stenosis (2023) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Activities of daily living (primary outcome) · participants after stroke Trunk training following stroke (2023) · Cochrane | no estimate extracted | 5 studies · 283 participants | Very low |
Intervention NR Arm‐hand activity · participants after stroke Trunk training following stroke (2023) · Cochrane | no estimate extracted | 3 studies · 112 participants | Very low |
Intervention NR Standing balance · participants after stroke Trunk training following stroke (2023) · Cochrane | no estimate extracted | 22 studies · 917 participants | Very low |
Intervention NR Walking ability · participants after stroke Trunk training following stroke (2023) · Cochrane | no estimate extracted | 19 studies · 535 participants | Low |
Intervention NR Quality of life after stroke · participants after stroke Trunk training following stroke (2023) · Cochrane | no estimate extracted | 2 studies · 111 participants | Very low |
Intervention NR Death and serious adverse events, including falls · participants after stroke Trunk training following stroke (2023) · Cochrane | no estimate extracted | 10 studies · 378 participants | Low |
Intervention NR Trunk function · participants after stroke Trunk training following stroke (2023) · Cochrane | no estimate extracted | 14 studies · 466 participants | Very low |
Intervention NR Arm‐hand activity · participants after stroke Trunk training following stroke (2023) · Cochrane | no estimate extracted | 1 study · 30 participants | Very low |
Intervention NR Standing balance · participants after stroke Trunk training following stroke (2023) · Cochrane | no estimate extracted | 11 studies · 410 participants | Very low |
Intervention NR Walking ability · participants after stroke Trunk training following stroke (2023) · Cochrane | no estimate extracted | 11 studies · 383 participants | Very low |
Intervention NR Quality of life after stroke · participants after stroke Trunk training following stroke (2023) · Cochrane | no estimate extracted | 2 studies · 108 participants | Very low |
Intervention NR Death and serious adverse events, including falls · participants after stroke Trunk training following stroke (2023) · Cochrane | no estimate extracted | 6 studies · 201 participants | Very low |
Intervention NR Activities of daily living (primary outcome) · participants after stroke Trunk training following stroke (2023) · Cochrane | no estimate extracted | 9 studies · 229 participants | Very low |
Intervention NR Trunk function · participants after stroke Trunk training following stroke (2023) · Cochrane | no estimate extracted | 36 studies · 1217 participants | Very low |
Thrombo‐aspiration alone vs stent‐retrieval thrombectomy alone Functional independence at 3 months (mRS 0 to 2) (primary outcome) · people with acute ischemic stroke Different types of percutaneous endovascular interventions for acute ischemic stroke (2023) · Cochrane | RR 0.97 [0.82, 1.13] | 2 studies · 633 participants | High |