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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

2,653 questions in 194 reviews · Gynaecology and Fertility

current versions
No studies 531 · 20%Ungraded 76 · 2.9%Very low 826 · 31.1%Low 855 · 32.2%Moderate 341 · 12.9%High 24 · 0.9%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
IVF vs expectant management
Miscarriage rate per woman randomised · women with unexplained subfertility
In vitro fertilisation for unexplained subfertility (2023) · Cochrane
no estimate extractedNRNo studies
IVF vs unstimulated IUI
Live birth rate per woman randomised · women with unexplained subfertility
In vitro fertilisation for unexplained subfertility (2023) · Cochrane
OR 2.47 [1.19, 5.12]2 studies · 156 participantsLow
IVF vs unstimulated IUI
Clinical pregnancy rate per woman randomised · women with unexplained subfertility
In vitro fertilisation for unexplained subfertility (2023) · Cochrane
OR 4.83 [0.94, 24.95]1 study · 43 participantsVery low
IVF vs unstimulated IUI
Multiple pregnancy rate per woman randomised · women with unexplained subfertility
In vitro fertilisation for unexplained subfertility (2023) · Cochrane
OR 1.03 [0.04, 27.29]1 study · 43 participantsVery low
IVF vs unstimulated IUI
OHSS rate per woman randomised · women with unexplained subfertility
In vitro fertilisation for unexplained subfertility (2023) · Cochrane
no estimate extractedNRNo studies
Vaginal hysterectomy vs abdominal hysterectomy
Return to normal activities (days) · patients with benign gynaecological disease
Surgical approach to hysterectomy for benign gynaecological disease (2023) · Cochrane
no estimate extracted4 studies · 274 participantsModerate
Laparoscopic hysterectomy vs abdominal hysterectomy
Major short‐term complications (dichotomous) · patients with benign gynaecological disease
Surgical approach to hysterectomy for benign gynaecological disease (2023) · Cochrane
OR 1.43 [0.67, 3.04]9 studies · 852 participantsLow
Laparoscopic hysterectomy vs vaginal hysterectomy
Return to normal activities (days) · patients with benign gynaecological disease
Surgical approach to hysterectomy for benign gynaecological disease (2023) · Cochrane
no estimate extracted3 studies · 238 participantsLow
Laparoscopic hysterectomy vs vaginal hysterectomy
Long‐term outcomes · patients with benign gynaecological disease
Surgical approach to hysterectomy for benign gynaecological disease (2023) · Cochrane
no estimate extractedNRNo studies
Laparoscopic hysterectomy vs vaginal hysterectomy
Long‐term complications (dichotomous) · patients with benign gynaecological disease
Surgical approach to hysterectomy for benign gynaecological disease (2023) · Cochrane
OR 1 [0.25, 4.07]3 studies · 248 participantsLow
Laparoscopic hysterectomy vs vaginal hysterectomy
Intra‐operative visceral injury (dichotomous) · patients with benign gynaecological disease
Surgical approach to hysterectomy for benign gynaecological disease (2023) · Cochrane
OR 0.93 [0.37, 2.33]10 studies · 1237 participantsLow
Laparoscopic hysterectomy vs vaginal hysterectomy
Major short‐term complications (dichotomous) · patients with benign gynaecological disease
Surgical approach to hysterectomy for benign gynaecological disease (2023) · Cochrane
OR 0.98 [0.22, 4.39]4 studies · 276 participantsLow
Robotic hysterectomy vs laparoscopic hysterectomy
Return to normal activities (days) · patients with benign gynaecological disease
Surgical approach to hysterectomy for benign gynaecological disease (2023) · Cochrane
no estimate extracted1 study · 100 participantsVery low
Robotic hysterectomy vs laparoscopic hysterectomy
Long‐term outcomes · patients with benign gynaecological disease
Surgical approach to hysterectomy for benign gynaecological disease (2023) · Cochrane
no estimate extractedNRNo studies
Robotic hysterectomy vs laparoscopic hysterectomy
Long‐term complications (dichotomous) · patients with benign gynaecological disease
Surgical approach to hysterectomy for benign gynaecological disease (2023) · Cochrane
no estimate extractedNRNo studies
Robotic hysterectomy vs laparoscopic hysterectomy
Intra‐operative visceral injury (dichotomous) · patients with benign gynaecological disease
Surgical approach to hysterectomy for benign gynaecological disease (2023) · Cochrane
no estimate extractedNRNo studies
Vaginal hysterectomy vs abdominal hysterectomy
Long‐term outcomes · patients with benign gynaecological disease
Surgical approach to hysterectomy for benign gynaecological disease (2023) · Cochrane
OR 2.69 [0.5, 14.42]1 study · 119 participantsVery low
Robotic hysterectomy vs laparoscopic hysterectomy
Major short‐term complications (dichotomous) · patients with benign gynaecological disease
Surgical approach to hysterectomy for benign gynaecological disease (2023) · Cochrane
no estimate extractedNRNo studies
Single‐port laparoscopic hysterectomy vs laparoscopic hysterectomy
Return to normal activities (days) · patients with benign gynaecological disease
Surgical approach to hysterectomy for benign gynaecological disease (2023) · Cochrane
no estimate extractedNRNo studies
Single‐port laparoscopic hysterectomy vs laparoscopic hysterectomy
Long‐term outcomes · patients with benign gynaecological disease
Surgical approach to hysterectomy for benign gynaecological disease (2023) · Cochrane
no estimate extractedNRNo studies
Single‐port laparoscopic hysterectomy vs laparoscopic hysterectomy
Long‐term complications (dichotomous) · patients with benign gynaecological disease
Surgical approach to hysterectomy for benign gynaecological disease (2023) · Cochrane
no estimate extractedNRNo studies
Single‐port laparoscopic hysterectomy vs laparoscopic hysterectomy
Intra‐operative visceral injury (dichotomous) · patients with benign gynaecological disease
Surgical approach to hysterectomy for benign gynaecological disease (2023) · Cochrane
OR 3.51 [0.14, 89.42]1 study · 64 participantsVery low
Single‐port laparoscopic hysterectomy vs laparoscopic hysterectomy
Major short‐term complications (dichotomous) · patients with benign gynaecological disease
Surgical approach to hysterectomy for benign gynaecological disease (2023) · Cochrane
no estimate extractedNRNo studies
Total laparoscopic hysterectomy vs laparoscopic‐assisted vaginal hysterectomy
Return to normal activities (days) · patients with benign gynaecological disease
Surgical approach to hysterectomy for benign gynaecological disease (2023) · Cochrane
no estimate extractedNRNo studies
Total laparoscopic hysterectomy vs laparoscopic‐assisted vaginal hysterectomy
Long‐term outcomes · patients with benign gynaecological disease
Surgical approach to hysterectomy for benign gynaecological disease (2023) · Cochrane
no estimate extractedNRNo studies
Total laparoscopic hysterectomy vs laparoscopic‐assisted vaginal hysterectomy
Long‐term complications (dichotomous) · patients with benign gynaecological disease
Surgical approach to hysterectomy for benign gynaecological disease (2023) · Cochrane
no estimate extractedNRNo studies
Total laparoscopic hysterectomy vs laparoscopic‐assisted vaginal hysterectomy
Intra‐operative visceral injury (dichotomous) · patients with benign gynaecological disease
Surgical approach to hysterectomy for benign gynaecological disease (2023) · Cochrane
OR 0.72 [0.06, 8.27]2 studies · 161 participantsLow
Vaginal hysterectomy vs abdominal hysterectomy
Long‐term complications (dichotomous) · patients with benign gynaecological disease
Surgical approach to hysterectomy for benign gynaecological disease (2023) · Cochrane
OR 3.2 [0.32, 31.9]2 studies · 177 participantsLow
Total laparoscopic hysterectomy vs laparoscopic‐assisted vaginal hysterectomy
Major short‐term complications (dichotomous) · patients with benign gynaecological disease
Surgical approach to hysterectomy for benign gynaecological disease (2023) · Cochrane
OR 0.28 [0.03, 2.45]1 study · 101 participantsVery low
V‐NOTES vs laparoscopic hysterectomy
Return to normal activities (days) · patients with benign gynaecological disease
Surgical approach to hysterectomy for benign gynaecological disease (2023) · Cochrane
no estimate extractedNRNo studies
V‐NOTES vs laparoscopic hysterectomy
Long‐term outcomes · patients with benign gynaecological disease
Surgical approach to hysterectomy for benign gynaecological disease (2023) · Cochrane
no estimate extractedNRNo studies
V‐NOTES vs laparoscopic hysterectomy
Long‐term complications (dichotomous) · patients with benign gynaecological disease
Surgical approach to hysterectomy for benign gynaecological disease (2023) · Cochrane
no estimate extractedNRNo studies
V‐NOTES vs laparoscopic hysterectomy
Intra‐operative visceral injury (dichotomous) · patients with benign gynaecological disease
Surgical approach to hysterectomy for benign gynaecological disease (2023) · Cochrane
OR 3.09 [0.12, 78.41]2 studies · 96 participantsLow
V‐NOTES vs laparoscopic hysterectomy
Major short‐term complications (dichotomous) · patients with benign gynaecological disease
Surgical approach to hysterectomy for benign gynaecological disease (2023) · Cochrane
no estimate extractedNRNo studies
Vaginal hysterectomy vs abdominal hysterectomy
Intra‐operative visceral injury (dichotomous) · patients with benign gynaecological disease
Surgical approach to hysterectomy for benign gynaecological disease (2023) · Cochrane
OR 1.62 [0.52, 4.99]7 studies · 697 participantsLow
Vaginal hysterectomy vs abdominal hysterectomy
Major short‐term complications (dichotomous) · patients with benign gynaecological disease
Surgical approach to hysterectomy for benign gynaecological disease (2023) · Cochrane
OR 3.14 [0.48, 20.55]3 studies · 216 participantsLow
Laparoscopic hysterectomy vs abdominal hysterectomy
Return to normal activities (days) · patients with benign gynaecological disease
Surgical approach to hysterectomy for benign gynaecological disease (2023) · Cochrane
no estimate extracted7 studies · 618 participantsLow
Laparoscopic hysterectomy vs abdominal hysterectomy
Long‐term outcomes · patients with benign gynaecological disease
Surgical approach to hysterectomy for benign gynaecological disease (2023) · Cochrane
OR 0.65 [0.32, 1.3]1 study · 166 participantsVery low
Laparoscopic hysterectomy vs abdominal hysterectomy
Long‐term complications (dichotomous) · patients with benign gynaecological disease
Surgical approach to hysterectomy for benign gynaecological disease (2023) · Cochrane
OR 0.94 [0.49, 1.82]3 studies · 343 participantsLow
Laparoscopic hysterectomy vs abdominal hysterectomy
Intra‐operative visceral injury(dichotomous) · patients with benign gynaecological disease
Surgical approach to hysterectomy for benign gynaecological disease (2023) · Cochrane
OR 1.68 [0.88, 3.22]15 studies · 2298 participantsLow
Drospirenone plus ethinylestradiol vs placebo
Mean daily rating of problem severity (lower score is better) · women with premenstrual syndrome (most met DSM‐V criteria for premenstrual dysphoric disorder (PMDD))
Oral contraceptives containing drospirenone for premenstrual syndrome (2023) · Cochrane
no estimate extracted2 studies · 513 participantsLow
Drospirenone plus ethinylestradiol vs placebo
Mean change in daily rating of functional impairment: reduction of productivity (lower score is better) · women with premenstrual syndrome (most met DSM‐V criteria for premenstrual dysphoric disorder (PMDD))
Oral contraceptives containing drospirenone for premenstrual syndrome (2023) · Cochrane
no estimate extracted2 studies · 432 participantsLow
Drospirenone plus ethinylestradiol vs placebo
Mean change in daily rating of functional impairment: social activities (lower score is better) · women with premenstrual syndrome (most met DSM‐V criteria for premenstrual dysphoric disorder (PMDD))
Oral contraceptives containing drospirenone for premenstrual syndrome (2023) · Cochrane
no estimate extracted2 studies · 432 participantsLow
Drospirenone plus ethinylestradiol vs placebo
Mean change in daily rating of functional impairment: relationship interference (lower score is better) · women with premenstrual syndrome (most met DSM‐V criteria for premenstrual dysphoric disorder (PMDD))
Oral contraceptives containing drospirenone for premenstrual syndrome (2023) · Cochrane
no estimate extracted2 studies · 432 participantsLow
Drospirenone plus ethinylestradiol vs placebo
Changes in Premenstrual Tension Scale scores (observer‐rated; lower score is better) · women with premenstrual syndrome (most met DSM‐V criteria for premenstrual dysphoric disorder (PMDD))
Oral contraceptives containing drospirenone for premenstrual syndrome (2023) · Cochrane
no estimate extracted1 study · 387 participantsLow
Drospirenone plus ethinylestradiol vs placebo
Changes in Premenstrual Tension Scale scores (self‐rated; lower score is better) · women with premenstrual syndrome (most met DSM‐V criteria for premenstrual dysphoric disorder (PMDD))
Oral contraceptives containing drospirenone for premenstrual syndrome (2023) · Cochrane
no estimate extracted2 studies · 438 participantsLow
Drospirenone plus ethinylestradiol vs placebo
Withdrawal due to adverse events · women with premenstrual syndrome (most met DSM‐V criteria for premenstrual dysphoric disorder (PMDD))
Oral contraceptives containing drospirenone for premenstrual syndrome (2023) · Cochrane
OR 3.41 [2.01, 5.78]4 studies · 776 participantsLow
Statin vs placebo
Resumption of menstrual regularity (menstrual cycle length in days) · women with polycystic ovary syndrome not actively trying to conceive
Statins for women with polycystic ovary syndrome not actively trying to conceive (2023) · Cochrane
no estimate extracted1 study · 37 participantsVery low
Statin plus metformin vs metformin alone
Improvement in acne severity (scale of 0–3) after 6 months' treatment · women with polycystic ovary syndrome not actively trying to conceive
Statins for women with polycystic ovary syndrome not actively trying to conceive (2023) · Cochrane
no estimate extracted1 study · 69 participantsVery low
Statin plus metformin vs metformin alone
Improvement in testosterone level (nmol/L) after 6 months' treatment · women with polycystic ovary syndrome not actively trying to conceive
Statins for women with polycystic ovary syndrome not actively trying to conceive (2023) · Cochrane
no estimate extracted1 study · 69 participantsVery low