Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

92 questions · 95 findings · 21 reviews

No studies found 8 · 8.4%GRADE not reported 5 · 5.3%Very low 26 · 27.4%Low 35 · 36.8%Moderate 19 · 20%High 2 · 2.1%

Summary of findings. Surgery (percutaneous wire fixation) vs not surgery (cast only)

'Treatment failure': various secondary procedures such as remanipulation for early loss of position; early or more complex wire removal ( · children with displaced distal radius fracture with intact or involved or displaced ulna fracture (both‐bone fracture)

It is very uncertain whether summary of findings. Surgery (percutaneous wire fixation) changes 'Treatment failure': various secondary procedures such as… compared with not surgery (cast only) (very low certainty).

1 finding from 1 review

Intervention not reported

Prevalence of psychological trauma (short term: up to 3 months postpartum) Measured by various scales ‐ Impact of Event Scale (IES), MINI‐PTSD · Women of any age who had given birth within one month of the intervention being offered

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Prevalence of depression or depressive symptoms (short term: up to 3 months postpartum) Measured by various scales ‐ EPDS, HADS · Women of any age who had given birth within one month of the intervention being offered

The review found no eligible studies for this question.

1 finding from 1 review

Intramedullary fixation vs open reduction and internal fixation with plate

Function (overall) Various tools · adults (aged ≥ 16 years) with acute middle third clavicle fractures

Intramedullary fixation may leads to higher function or disability (overall) Various tools (Constant score and… compared with open reduction and internal fixation with plate (low certainty).

1 finding from 1 review

Intramedullary fixation vs open reduction and internal fixation with plate

Adverse events ‐ total of adverse events (various: mainly infection; cosmetic result ‐ e.g. prominent metalwork ‐ and symptomatic hardware) · adults (aged ≥ 16 years) with acute middle third clavicle fractures

It is very uncertain whether intramedullary fixation changes adverse events ‐ total of adverse events (various: mainly infection;… compared with open reduction and internal fixation with plate (very low certainty).

1 finding from 1 review

Intervention not reported

Symptom Level: Social Interaction Various measures, including: Autism Diagnostic Observation Schedule (ADOS) Communication and Symbolic Behaviour Scale (CSBS) Early Social Communication Scales (ESCS) PDD‐BI social approach subscale Precursors of J... · People with autism spectrum disorder
1 finding from 1 review

Intervention not reported

Total studies: 42 Total participants: 14,626 · people with chronic pain Interventions: desvenlafaxine high dose (≥ 50 mg); duloxetine low dose (< 60 mg), standard dose (60 mg), and high…

The intervention led to lower total studies: 42 Total participants: 14,626; GRADE not reported.

1 finding from 1 review