Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

94 questions · 101 findings · 8 reviews · Metabolic and Endocrine Disorders

No studies found 29 · 28.7%GRADE not reported 4 · 4%Very low 37 · 36.6%Low 18 · 17.8%Moderate 12 · 11.9%High 1 · 1%

Intraoperative neuromonitoring vs visual nerve identification only during thyroidectomy

Adverse events other than RILN palsy (participants) Definition: transient hypoparathyroidism

It is very uncertain whether intraoperative neuromonitoring changes adverse events other than RILN palsy (participants) Definition:… compared with visual nerve identification only during thyroidectomy (very low certainty).

1 finding from 1 review

Total thyroidectomy vs subtotal thyroidectomy

R ate of recurrent hyperthyroidism [measured by thyroid function tests]

Total thyroidectomy probably leads to lower rate of recurrent hyperthyroidism [measured by thyroid function tests] compared with subtotal thyroidectomy (moderate certainty).

2 findings from 1 review

Total thyroidectomy vs subtotal thyroidectomy

Permanent recurrent laryngeal nerve palsy [patient reported, confirmation by laryngoscopy]

Total thyroidectomy showed no clear difference in permanent recurrent laryngeal nerve palsy [patient reported,… compared with bilateral subtotal thyroidectomy (low certainty).

2 findings from 1 review

Total thyroidectomy vs subtotal thyroidectomy

Permanent hypocalcaemia/hypoparathyroidism [measured by serum calcium levels]

Total thyroidectomy showed no clear difference in permanent hypocalcaemia/hypoparathyroidism [measured by serum… compared with bilateral subtotal thyroidectomy (low certainty).

2 findings from 1 review

Bilateral subtotal thyroidectomy vs the Dunhill procedure

Permanent recurrent laryngeal nerve palsy [patient reported, confirmation by laryngoscopy]

Bilateral subtotal thyroidectomy showed no clear difference in permanent recurrent laryngeal nerve palsy [patient reported,… compared with the Dunhill procedure (low certainty).

1 finding from 1 review

Total thyroidectomy vs subtotal thyroidectomy

Regression of Graves' ophthalmopathy [ophthalmology assessment]

Total thyroidectomy showed no clear difference in regression of Graves' ophthalmopathy [ophthalmology assessment] compared with subtotal thyroidectomy (low certainty).

2 findings from 1 review