Cochrane · systematic review · CD012483

Intraoperative neuromonitoring versus visual nerve identification for prevention of recurrent laryngeal nerve injury in adults undergoing thyroid surgery

Cirocchi, R, Arezzo, A, D'Andrea, V, et al. · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library

Metabolic and Endocrine DisordersAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
5
No studies
2
Included studies
NR
No studies 2 · 28.6%Ungraded 0 · 0%Very low 4 · 57.1%Low 0 · 0%Moderate 1 · 14.3%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Intraoperative neuromonitoring compared to visual nerve identification only during thyroidectomy

7 questions
OutcomeEffectEvidenceStatus / GRADE
Permanent RILN palsy (nerves) Definition: injury detected clinically, by laryngoscopy or both, in which the motility of the vocal cords did not recover within 6 months after surgery
Intraoperative neuromonitoring vs visual nerve identification only during thyroidectomy
RR 0.77 [0.33, 1.77]4 studies · 2895 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Transient RILN palsy (nerves) Definition: injury detected clinically, by laryngoscopy or both, in which the motility of the vocal cords recovered within 6 months after surgery
Intraoperative neuromonitoring vs visual nerve identification only during thyroidectomy
RR 0.62 [0.35, 1.08]4 studies · 2895 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Health‐related quality of life
Intraoperative neuromonitoring vs visual nerve identification only during thyroidectomy
no estimate extractedNRNo studies
Adverse events other than RILN palsy (participants) Definition: transient hypoparathyroidism
Intraoperative neuromonitoring vs visual nerve identification only during thyroidectomy
RR 1.25 [0.45, 3.47]2 studies · 286 participantsVery low
Downgraded: imprecision, inconsistency
Operative time (min) Definition: time from the first skin incision to skin closure
Intraoperative neuromonitoring vs visual nerve identification only during thyroidectomy
no estimate extracted3 studies · 1251 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
All‐cause mortality (nerves)
Intraoperative neuromonitoring vs visual nerve identification only during thyroidectomy
no estimate extracted3 studies · 1438 participantsModerate
Downgraded: imprecision
Socioeconomic effects
Intraoperative neuromonitoring vs visual nerve identification only during thyroidectomy
no estimate extractedNRNo studies