Primary outcome: subjective symptom score (mean) ‐ 3 hours after dosing · adult patients with the common cold
1 finding from 1 review
General well‐being · adult patients with the common cold
1 finding from 1 review
Secondary outcome: all adverse events · adult patients with the common cold
1 finding from 1 review
HIV seroconversion ‐ penicillin vs single‐dose azithromycin · patients with syphilis
1 finding from 1 review
Participant‐reported pain relief of 50% or greater · adults (mean study ages 23 to 67 years) with acute postoperative pain after abdominal/pelvic, dental or orthopedic surgeries
It is very uncertain whether intravenous ketorolac changes number of participants with at least 50% pain relief over 4 hours compared with placebo (very low certainty).
1 finding from 1 review
Number of women requiring rescue medication · adults (mean study ages 23 to 67 years) with acute postoperative pain after abdominal/pelvic, dental or orthopedic surgeries
It is very uncertain whether intravenous ketorolac changes number of participants using rescue medication over 4 or 6 hours… compared with another NSAID (very low certainty).
1 finding from 1 review
Number of participants reporting an adverse event · adults (mean study ages 23 to 67 years) with acute postoperative pain after abdominal/pelvic, dental or orthopedic surgeries
Intravenous ketorolac showed no clear difference in number of participants reporting any adverse event compared with another NSAID (moderate certainty).
1 finding from 1 review
Number of participants experiencing any serious adverse events · adults (mean study ages 23 to 67 years) with acute postoperative pain after abdominal/pelvic, dental or orthopedic surgeries
Intravenous ketorolac showed no clear difference in number of participants experiencing a serious adverse event compared with another NSAID (low certainty).
1 finding from 1 review
Relief of pain · adults (mean study ages 23 to 67 years) with acute postoperative pain after abdominal/pelvic, dental or orthopedic surgeries
Intravenous ketorolac may leads to higher number of participants with at least 50% pain relief over 6 hours compared with placebo (low certainty).
1 finding from 1 review
Median (mean) time to use of rescue medication · adults (mean study ages 23 to 67 years) with acute postoperative pain after abdominal/pelvic, dental or orthopedic surgeries
1 finding from 1 review
Use of rescue medication · adults (mean study ages 23 to 67 years) with acute postoperative pain after abdominal/pelvic, dental or orthopedic surgeries
It is very uncertain whether intravenous ketorolac changes number of participants using rescue medication over 4 or 6 hours… compared with placebo (very low certainty).
1 finding from 1 review
Number of participants reporting an adverse event · adults (mean study ages 23 to 67 years) with acute postoperative pain after abdominal/pelvic, dental or orthopedic surgeries
Intravenous ketorolac showed no clear difference in number of participants reporting any adverse event compared with placebo (moderate certainty).
1 finding from 1 review
Number of participants experiencing any serious adverse events · adults (mean study ages 23 to 67 years) with acute postoperative pain after abdominal/pelvic, dental or orthopedic surgeries
Intravenous ketorolac showed no clear difference in number of participants experiencing a serious adverse event compared with placebo (low certainty).
1 finding from 1 review
Participant‐reported pain relief of 50% or greater · adults (mean study ages 23 to 67 years) with acute postoperative pain after abdominal/pelvic, dental or orthopedic surgeries
Intravenous ketorolac showed no clear difference in number of participants with at least 50% pain relief over 4 hours compared with another NSAID (low certainty).
1 finding from 1 review
Relief of pain · adults (mean study ages 23 to 67 years) with acute postoperative pain after abdominal/pelvic, dental or orthopedic surgeries
Intravenous ketorolac showed no clear difference in number of participants with at least 50% pain relief over 6 hours compared with another NSAID (moderate certainty).
1 finding from 1 review
Median (mean) time to use of rescue medication · adults (mean study ages 23 to 67 years) with acute postoperative pain after abdominal/pelvic, dental or orthopedic surgeries
1 finding from 1 review
At least 50% reduction in pain · health problem or population
It is very uncertain whether summary of Findings Table ‐ Ibuprofen changes number of participants with at least 50% pain relief at 4 hours compared with placebo (very low certainty).
2 findings from 1 review
Median (mean) time to use of rescue medication · health problem or population
1 finding from 1 review
Number of participants reporting an adverse event · health problem or population
It is very uncertain whether summary of Findings Table ‐ Ibuprofen 300 mg changes number of participants reporting or experiencing any adverse event compared with active comparator (acetaminophen) (very low certainty).
1 finding from 1 review
Number of participants experiencing any serious adverse events · health problem or population
1 finding from 1 review
no estimate extracted
1 study · 1 participants
Very low