Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

116 questions · 117 findings · 13 reviews · Schizophrenia

No studies found 24 · 20.5%GRADE not reported 14 · 12%Very low 20 · 17.1%Low 32 · 27.4%Moderate 27 · 23.1%High 0 · 0%

QUETIAPINE vs Typical antipsychotics

Global state: No clinically significant response (as defined by the original studies) · patients with schizophrenia

Quetiapine showed no clear difference in global state No clinical significant response as defined by the… compared with typical antipsychotics (moderate certainty).

1 finding from 1 review

SWITCHING ‐ NEW ANTIPSYCHOTIC REGIMEN vs CONTINUATION ON PREVIOUS REGIMEN: 1b. NEW ATYPICAL from OLANZAPINE ‐ medium term (3‐12 months)

Physiological measures: 1c. Average fasting glucose change ‐ switching to aripiprazole and quetiapine · patients with people with schizophrenia who have neuroleptic‐induced weight or metabolic problems
1 finding from 1 review