Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

125 questions · 126 findings · 20 reviews

No studies found 29 · 23%GRADE not reported 23 · 18.3%Very low 20 · 15.9%Low 36 · 28.6%Moderate 15 · 11.9%High 3 · 2.4%

Turning position vs supine under phototherapy

Rate of decline of serum bilirubin (micromol/L/hr) · term and preterm neonates with hyperbilirubinaemia

Turning position showed no clear difference in rate of fall of serum total bilirubin at 24 hours of starting… compared with supine under phototherapy (low certainty).

1 finding from 1 review

Sunlight (with or without filters or amplification) vs other sources of phototherapy

Use of conventional phototherapy, if sunlight (with or without filters or amplification) was first used for prevention or early treatmentc · infants with confirmed hyperbilirubinemia

The review found no eligible studies for this question.

1 finding from 1 review

Sunlight (with or without filters or amplification) vs other sources of phototherapy

Hyperthermia while receiving sunlight or conventional phototherapyg · infants with confirmed hyperbilirubinemia

Sunlight (with or without filters or amplification) probably leads to higher hyperthermia while receiving sunlight or conventional phototherapyg compared with other sources of phototherapy (moderate certainty).

1 finding from 1 review

Sunlight (with or without filters or amplification) vs other sources of phototherapy

Hypothermia while receiving sunlight or conventional phototherapyk · infants with confirmed hyperbilirubinemia

Sunlight (with or without filters or amplification) showed no clear difference in hypothermia while receiving sunlight or conventional phototherapyk compared with other sources of phototherapy (moderate certainty).

1 finding from 1 review

Any topical or systemic intervention (topical/systemic steroids, ciclosporin, tacrolimus, retinoids, anti-malarials, biologics, phototherapy, surgery) vs Placebo, no treatment, another active intervention, or a different dose of the same intervention

Eating a normally varied diet · People of any age with erosive lichen planus affecting the oral, anogenital, and/or oesophageal regions

The review found no eligible studies for this question.

1 finding from 1 review

Any topical or systemic intervention (topical/systemic steroids, ciclosporin, tacrolimus, retinoids, anti-malarials, biologics, phototherapy, surgery) vs Placebo, no treatment, another active intervention, or a different dose of the same intervention

Restoration of sexual activity · People of any age with erosive lichen planus affecting the oral, anogenital, and/or oesophageal regions

The review found no eligible studies for this question.

1 finding from 1 review

Any topical or systemic intervention (topical/systemic steroids, ciclosporin, tacrolimus, retinoids, anti-malarials, biologics, phototherapy, surgery) vs Placebo, no treatment, another active intervention, or a different dose of the same intervention

Reduction in number of flares · People of any age with erosive lichen planus affecting the oral, anogenital, and/or oesophageal regions

The review found no eligible studies for this question.

1 finding from 1 review

Any topical or systemic intervention (topical/systemic steroids, ciclosporin, tacrolimus, retinoids, anti-malarials, biologics, phototherapy, surgery) vs Placebo, no treatment, another active intervention, or a different dose of the same intervention

Reduction in severity of flares · People of any age with erosive lichen planus affecting the oral, anogenital, and/or oesophageal regions

The review found no eligible studies for this question.

1 finding from 1 review

Summary of findings table ‐ Transcutaneous bilirubin (TcB) screening vs visual assessment

Readmission for phototherapy for hyperbilirubinemia · newborns for hyperbilirubinemia

Summary of findings table ‐ Transcutaneous bilirubin (TcB) screening probably leads to lower readmission for phototherapy for hyperbilirubinemia compared with visual assessment (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Transcutaneous bilirubin (TcB) screening vs visual assessment

Phototherapy before hospital discharge · newborns for hyperbilirubinemia

Summary of findings table ‐ Transcutaneous bilirubin (TcB) screening probably leads to higher phototherapy before hospital discharge compared with visual assessment (moderate certainty).

1 finding from 1 review

Sunlight (with or without filters or amplification) vs no treatment

Use of conventional phototherapy, if sunlight (with or without filters or amplification) was first used for prevention or early treatmentc · term and late preterm neonates

The review found no eligible studies for this question.

1 finding from 1 review

Active vs expectant management of the third stage of labour (all women)

Neonatal jaundice requiring phototherapy or exchange transfusion · all women who expected a vaginal birth at 24 weeks' gestation or later and their babies

It is very uncertain whether active changes neonatal jaundice requiring phototherapy or exchange transfusion compared with expectant management of the third stage of labour (all women) (very low certainty).

1 finding from 1 review

Prebiotic vs no prebiotics

Treatment with phototherapy · Neonates, including term neonates (gestational age ≥ 37 weeks), late preterm neonates (35 to 37 weeks' gestation) and preterm neonates (<…

Feeding supplementation with prebiotics may leads to lower treatment with phototherapy compared with no prebiotics (low certainty).

1 finding from 1 review