Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,155 questions · 1,191 findings · 195 reviews · Headline outcomes only

No studies found 209 · 17.5%GRADE not reported 51 · 4.3%Very low 256 · 21.5%Low 273 · 22.9%Moderate 284 · 23.8%High 118 · 9.9%

Inhaled NO at moderate vs severe criteria

Neurodevelopmental disability at 18 to 24 months among survivors · respiratory failure in infants born at or near term

Inhaled NO at moderate showed no clear difference in neurodevelopmental disability at 18 to 24 months among survivors compared with severe criteria (moderate certainty).

1 finding from 1 review

Dextrose gel vs placebo

Major neurological disability at 2 years of age (Defined as any of the following: legal blindness, sensorineural deafness requiring hearing aids, moderate or severe cerebral palsy or developmental delay/intellectual impairment (developmental quoti... · newborn infants at risk of neonatal hypoglycaemia

Dextrose gel showed no clear difference in major neurological disability at 2 years of age (Defined as any of… compared with placebo (low certainty).

1 finding from 1 review