Remission or response (as defined in trial) · patients with depressive disorders in children and adolescents
Second generation antidepressant probably leads to higher remission or response (as defined in trial) compared with placebo (by medication) (moderate certainty).
1 finding from 1 review
Suicide‐related outcomes Timing of outcome assessment: end of treatment (6 to 12 weeks treatment duration) · patients with depressive disorders in children and adolescents
Second generation antidepressant may leads to higher suicide‐related outcome compared with placebo (by medication) (low certainty).
1 finding from 1 review
Depressive symptoms · patients with depressive disorders in children and adolescents
1 finding from 1 review
Endpoint International Index of Erectile Function (IIEF) total scores (The IIEF is a self‐report measure with 15 questions examining erectile function, orgasmic function, sexual desire, and intercourse satisfaction. Maximum possible score 75) · people with antidepressant‐induced sexual dysfunction
1 finding from 1 review
Endpoint International Index of Erectile Function (IIEF) scores ‐ question 3: ability to achieve erection (Maximum score 5) · people with antidepressant‐induced sexual dysfunction
1 finding from 1 review
Endpoint International Index of Erectile Function (IIEF) scores ‐ intercourse satisfaction (questions 6, 7, 8) (Maximum score 15) · people with antidepressant‐induced sexual dysfunction
1 finding from 1 review
Effect on later sexual function · people with antidepressant‐induced sexual dysfunction
Sildenafil probably leads to lower clinical Global Impression ‐Sexual Function not "much/very much… compared with placebo (moderate certainty).
1 finding from 1 review
Dropout · people with antidepressant‐induced sexual dysfunction
Sildenafil showed no clear difference in dropouts (People leaving the trial early) compared with placebo (high certainty).
1 finding from 1 review
Endpoint scale total scores (150 mg twice daily dose) (Scales of sexual functioning. As studies used different scales to assess sexual functioning, differences are expressed as standardised mean differences (SMD)) · people with antidepressant‐induced sexual dysfunction
1 finding from 1 review
Effect on later sexual function · people with antidepressant‐induced sexual dysfunction
Bupropion showed no clear difference in 50% reduction in score on the Arizona Sexual Experiences Scale… compared with placebo (moderate certainty).
1 finding from 1 review
Dropout · people with antidepressant‐induced sexual dysfunction
Bupropion showed no clear difference in dropouts (People leaving the trial early) compared with placebo (high certainty).
1 finding from 1 review