Sensitivity analysis, meta‐regression analysis, second part · palliative participants with esophageal and GE‐junction carcinoma or gastric carcinoma
Summary of findings table (sensitivity analysis): interventions… probably leads to lower sensitivity analysis, meta‐regression analysis, second part compared with gastric carcinoma (moderate certainty).
1 finding from 1 review
Intervention not reported
Colonic transit rate (geometric centre of radioactive substance). Unit indicates position along with intestinal tract. Scale from: 1 (small intestine) to 5 (rectosigmoid area). · children with chronic constipation
1 finding from 1 review
Long‐term recurrence (> 5 years) · patients with oesophageal cancer
It is very uncertain whether non‐surgical changes long‐term recurrence (binary outcome) Local recurrence, surgical… compared with surgical treatment of oesophageal cancer (secondary outcomes) (very low certainty).
1 finding from 1 review
Long‐term recurrence (maximal · patients with oesophageal cancer
Non‐surgical showed no clear difference in long‐term recurrence (time‐to‐event outcome) Local recurrence,… compared with surgical treatment of oesophageal cancer (secondary outcomes) (low certainty).
1 finding from 1 review
Number of participants with worsening scores in corporal intestinal metaplasia · people with pre‐malignant lesions
Proton pump inhibitor showed no clear difference in number of participants with worsening scores in corporal intestinal… compared with control (low certainty).
1 finding from 1 review
Intervention not reported
Lymph node mets analysis ‐ N+ OS · patients with resectable gastric cancer
The intervention probably leads to lower lymph node mets analysis ‐ N+ OS (moderate certainty).
1 finding from 1 review
Intervention not reported
Lymph node mets analysis ‐ N‐ OS · patients with resectable gastric cancer
The intervention showed no clear difference in lymph node mets analysis ‐ N‐ OS (moderate certainty).
1 finding from 1 review
Systemic complications defined by the Atlanta Classification (organ failure including shock, pulmonary insufficiency, renal failure, and gastrointestinal bleeding; disseminated intravascular coagulation or severe metabolic disturbances) · patients with unselected patients with acute gallstone pancreatitis
Early routine ERCP strategy showed no clear difference in systemic complications defined by the Atlanta Classification (organ… compared with early conservative management with or without delayed or selective… (moderate certainty).
1 finding from 1 review
Recurrent and persistent bleeding overall rates with or without second‐look endoscopy Rebleeding (persistent or recurrent bleeding) · patients with high‐risk bleeding ulcers
Epinephrine probably leads to lower recurrent and persistent bleeding overall rates with or without… compared with epinephrine and any second endoscopic method (moderate certainty).
1 finding from 1 review
Surgery rate Number requiring emergency surgery · patients with high‐risk bleeding ulcers
Epinephrine probably leads to lower surgery rate Number requiring emergency surgery compared with epinephrine and any second endoscopic method (moderate certainty).
1 finding from 1 review
Mortality rate Number of deaths (30‐day mortality or in‐hospital mortality) · patients with high‐risk bleeding ulcers
Epinephrine probably leads to lower mortality rate Number of deaths (30‐day mortality or in‐hospital… compared with epinephrine and any second endoscopic method (moderate certainty).
1 finding from 1 review
Adverse effects of endoscopy therapy Adverse effects · patients with high‐risk bleeding ulcers
Epinephrine probably leads to higher adverse effects of endoscopy therapy Adverse effects compared with epinephrine and any second endoscopic method (moderate certainty).
1 finding from 1 review
UGIH‐related mortality · people with acute UGIH
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
SAEs · people with acute UGIH
1 finding from 1 review
All‐cause mortality · people with acute UGIH
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Visualisation of gastric mucosa · people with acute UGIH
It is very uncertain whether erythromycin plus nasogastric tube lavage changes visualisation of gastric mucosa compared with metoclopramide plus nasogastric tube lavage (very low certainty).
1 finding from 1 review
NSAEs · people with acute UGIH
1 finding from 1 review
Rebleeding · people with acute UGIH
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Blood transfusion · people with acute UGIH
1 finding from 1 review
Clinical improvement · adults with refractory, moderate‐to‐severe ulcerative colitis
Tacrolimus showed no clear difference in clinical improvement compared with beclometasone (low certainty).
1 finding from 1 review