Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,191 questions · 2,354 findings · 362 reviews

No studies found 323 · 13.7%GRADE not reported 382 · 16.2%Very low 555 · 23.6%Low 597 · 25.4%Moderate 345 · 14.7%High 152 · 6.5%

Early enteral nutrition within 24 hours of lower gastrointestinal surgery vs later commencement

Vomiting · lower gastrointestinal surgery

Early enteral nutrition within 24 hours of lower gastrointestinal… showed no clear difference in vomiting compared with later commencement (low certainty).

1 finding from 1 review

Early enteral nutrition within 24 hours of lower gastrointestinal surgery vs later commencement

Nausea · lower gastrointestinal surgery

Early enteral nutrition within 24 hours of lower gastrointestinal… showed no clear difference in nausea compared with later commencement (low certainty).

1 finding from 1 review

Early enteral nutrition within 24 hours of lower gastrointestinal surgery vs later commencement

Nausea and vomiting · lower gastrointestinal surgery

It is very uncertain whether early enteral nutrition within 24 hours of lower gastrointestinal… changes nausea and vomiting compared with later commencement (very low certainty).

1 finding from 1 review

IM injection vs IA injection

Improvement in lower limb perfusion: ABI · people with critical limb ischaemia

It is very uncertain whether IM injection changes improvement in lower limb perfusion: number of participants with… compared with IA injection (very low certainty).

1 finding from 1 review

IM injection vs IA injection

Improvement in lower limb perfusion: number of participants with improved TcO₂ reading · people with critical limb ischaemia

It is very uncertain whether IM injection changes improvement in lower limb perfusion: number of participants with… compared with IA injection (very low certainty).

1 finding from 1 review

Any intervention to manage relapse: fixed options (labial braces, lingual braces, fixed lingual wire) or removable options (Hawley's retainer with spring elastomeric module, Bloore removable aligner, other Hawley's retainer modifications, Invisalign, Clearstep) vs no intervention or another intervention

Assessment of the alignment of the lower front teeth using any method or index · Participants who previously underwent orthodontic treatment, with subsequent crowding (relapse) of the lower front teeth (lower incisors…

The review found no eligible studies for this question.

1 finding from 1 review

Any orthodontic and/or surgical treatment for Angle Class III malocclusion vs no intervention or another intervention

Correction of prominent lower front teeth / effectiveness of treatment (planned primary outcome) · Adults (16 years of age or older) with an Angle Class III malocclusion (prominent lower front teeth); people with syndromes, clefts or…

The review found no eligible studies for this question.

1 finding from 1 review
  • No included study measured the planned primary outcome. Discussion: 'The primary outcome proposed for this review was to evaluate the effectiveness of treatments for prognathism, but none of the studies conclusively…
    Studies not reported
    No studies found

Uric acid lowering therapies (UAR) vs Placebo, no intervention or usual care (with or without placebo)

Cardiovascular events · people with CKD

Uric acid lowering therapies (UAR) showed no clear difference in cardiovascular events compared with placebo, no treatment or usual care (low certainty).

1 finding from 1 review