Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

516 questions · 950 findings · 74 reviews · Dental caries

No studies found 35 · 3.7%GRADE not reported 831 · 87.5%Very low 38 · 4%Low 26 · 2.7%Moderate 13 · 1.4%High 7 · 0.7%

Low polymerization shrinkage resin composite (silorane, ormocer, bulk-fill or other modified-monomer composite) vs Conventional methacrylate-based resin composite

Marginal adaptation (clinically detectable deterioration) · People with permanent posterior teeth restored with class I or II direct restorations

At 60 months, marginal adaptation did not differ significantly between the composites (4 groups; ungraded).

5 findings from 1 review
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Low polymerization shrinkage resin composite (silorane, ormocer, bulk-fill or other modified-monomer composite) vs Conventional methacrylate-based resin composite

Secondary caries · People with permanent posterior teeth restored with class I or II direct restorations

No secondary caries was reported at 24 months in any of seven studies, so no meta-analysis was possible (ungraded).

2 findings from 1 review

Low polymerization shrinkage resin composite (silorane, ormocer, bulk-fill or other modified-monomer composite) vs Conventional methacrylate-based resin composite

Marginal discoloration · People with permanent posterior teeth restored with class I or II direct restorations

At 24 months, marginal discoloration did not differ significantly (7 groups; p = 0.77; ungraded).

4 findings from 1 review
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Low polymerization shrinkage resin composite (silorane, ormocer, bulk-fill or other modified-monomer composite) vs Conventional methacrylate-based resin composite

Retention (restoration loss) · People with permanent posterior teeth restored with class I or II direct restorations

At 24 months, retention did not differ significantly between the composites (6 studies; ungraded).

2 findings from 1 review

Low polymerization shrinkage resin composite (silorane, ormocer, bulk-fill or other modified-monomer composite) vs Conventional methacrylate-based resin composite

Postoperative sensitivity · People with permanent posterior teeth restored with class I or II direct restorations

Postoperative sensitivity at 12 months did not differ significantly between low polymerization shrinkage and methacrylate composites (OR 1.65, 95% CI 0.71 to 3.81; Moderate certainty).

2 findings from 1 review

Sociodemographic and behavioural factors (older age, lower education, lower income, poor oral hygiene/brushing, smoking, disadvantaged/slum residence, sex) vs Referent groups (younger, higher education/income, better oral hygiene, non-slum residence)

Determinants of oral diseases · Adult residents of slums and non-slum urban settings of LMICs

Age, education, income, oral-hygiene behaviour, dental-visit pattern and slum/disadvantaged residence are associated with oral disease; gender effects are disease-specific; ungraded.

1 finding from 1 review

Gum chewing (sugar-free) vs No chewing gum

Salivary flow rate · Elderly (>60 years) and medically compromised adults with xerostomia / dry mouth

Across 19 studies the effect of gum chewing on stimulated and/or unstimulated salivary flow rate was mixed (9 positive, 10 no effect); this broad outcome was not meta-analyzed.

1 finding from 1 review

Daily chewing gum for 2 weeks or longer vs No gum chewing or control

Salivary flow rate (unstimulated) · Elderly (>60 years) and medically compromised adults with xerostomia / dry mouth

codex

1 finding from 1 review

Gum chewing (sugar-free) vs No chewing gum

Salivary flow rate (unstimulated) · Elderly (>60 years) and medically compromised adults with xerostomia / dry mouth

In elderly and medically compromised people with xerostomia, chewing sugar-free gum daily for two or more weeks produces a small but statistically significant increase in unstimulated whole salivary flow rate versus no gum (SMD 0.44, 95% CI 0.22 to 0.66); certainty of evidence was not formally graded.

1 finding from 1 review

Flowable resin composite vs Fluoride-releasing resin-based sealant

Retention of sealant (complete or partial retention) · Children who were regular dental attenders with caries-free first or second primary molars (public health service clinic, Brazil)
1 finding from 1 review
  • Sealants for preventing dental caries in primary teeth 2022 · Cochrane All outcomes
    12 months
    Effect estimate not calculable. All sealants were completely or partially retained; 40 (1 RCT). Flowable composite: 39/40 completely retained (1 partially lost) at 6 months; resin-based: 33 completely and 7 partially…
    1 study · 40 participants
    Low

Low edentulism prevalence vs Not applicable

Oral health-related quality of life · people aged 60 years and older living in the community

No statistically significant difference in OHRQoL was reported by edentulism prevalence.

1 finding from 1 review