Renal failure · adults receiving intravenous fluids while undergoing major non‐cardiac surgery
It is very uncertain whether perioperative restrictive fluid therapy changes renal failure (during longest compared with goal‐directed fluid therapy (very low certainty).
1 finding from 1 review
Quality of surgical recovery assessed in any way (e.g. as a surgical recovery score) (during longest · adults receiving intravenous fluids while undergoing major non‐cardiac surgery
1 finding from 1 review
Duration of sensory block (we included all studies describing duration of sensory block regardless of how it was described) · peripheral nerve block
1 finding from 1 review
Incidence of serious adverse events (we used the NIH definition of adverse events. A serious event includes death, a life‐threatening event that requires hospitalization or prolonged hospitalization, disability or congenital anomaly) · peripheral nerve block
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · peripheral nerve block
3 findings from 1 review
no estimate extracted
3 studies · 217 participants
Low
no estimate extracted
5 studies · 309 participants
Moderate
no estimate extracted
3 studies · 227 participants
Low
Nausea · participants aged 6 months or older undergoing surgical procedures under general anaesthesia
Supplemental IV crystalloid probably leads to lower risk of PON, defined as the presence of subjective nausea, reported… compared with control IV crystalloid volume (moderate certainty).
1 finding from 1 review
Risk of POV, reported dichotomously by any discrete episodes of vomiting · participants aged 6 months or older undergoing surgical procedures under general anaesthesia
Supplemental IV crystalloid probably leads to lower risk of POV, reported dichotomously by any discrete episodes of… compared with control IV crystalloid volume (moderate certainty).
1 finding from 1 review
Risk of requiring pharmacologic treatment for PONV, reported dichotomously as the use of any medication intended to treat nausea or vomiting during the postoperative period · participants aged 6 months or older undergoing surgical procedures under general anaesthesia
Supplemental IV crystalloid probably leads to lower risk of requiring pharmacologic treatment for PONV, reported… compared with control IV crystalloid volume (moderate certainty).
1 finding from 1 review
Risk of unintended postoperative admission to hospital, reported dichotomously as admission to an inpatient unit of a participant after an intended ambulatory surgical procedure · participants aged 6 months or older undergoing surgical procedures under general anaesthesia
Supplemental IV crystalloid showed no clear difference in risk of unintended postoperative admission to hospital, reported… compared with control IV crystalloid volume (low certainty).
1 finding from 1 review
Risk of suffering a serious adverse event, reported dichotomously as the occurrence of any of: admission to high‐dependency unit, postoperative cardiac or respiratory complication, or death · participants aged 6 months or older undergoing surgical procedures under general anaesthesia
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Postoperative delirium (One study used DRS, three studies used CAM and in one study diagnostic tool was not reported) Time points were up to 4 days postoperatively
It is very uncertain whether summary of findings TIVA changes postoperative delirium (One study used DRS, three studies used CAM… compared with inhalational maintenance of anaesthesia (very low certainty).
1 finding from 1 review
Postoperative cognitive dysfunction (9 studies used MMSE, and 2 of these studies used additional diagnostic tools; 1 study used Trail Making Test and additional diagnostic tools; 3 studies did not report diagnostic tools) Time points were up to 30...
Summary of findings TIVA may leads to lower postoperative cognitive dysfunction (9 studies used MMSE, and 2 of… compared with inhalational maintenance of anaesthesia (low certainty).
1 finding from 1 review
Mortality at 30 days
It is very uncertain whether summary of findings TIVA changes mortality At 30 days compared with inhalational maintenance of anaesthesia (very low certainty).
1 finding from 1 review
Intraoperative hypotension (defined by study authors as change in MAP from baseline)
1 finding from 1 review
Length of stay in PACU
1 finding from 1 review
Length of hospital stay
1 finding from 1 review
Intervention not reported
Risk of hypothermia ‐ not reported · adults undergoing surgery.
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Mean core temperature, 60 minutes · adults undergoing surgery.
1 finding from 1 review
Intervention not reported
Mean core temperature, 120 minutes · adults undergoing surgery.
1 finding from 1 review
Intervention not reported
Mean core temperature at the end of surgery · adults undergoing surgery.
1 finding from 1 review