Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

179 questions · 184 findings · 37 reviews

No studies found 34 · 18.5%GRADE not reported 6 · 3.3%Very low 56 · 30.4%Low 56 · 30.4%Moderate 23 · 12.5%High 9 · 4.9%

Early active flexion plus controlled passive exercise regimen vs controlled passive exercise regimen following surgery

Tendon rupture · participants undergoing rehabilitation following surgery for flexor tendon injuries of the handa

It is very uncertain whether early active flexion plus controlled passive exercise regimen changes adverse event (tendon rupture) compared with early controlled passive exercise regimen (very low certainty).

1 finding from 1 review

Vitrectomy vs vitreous tap biopsy and antibiotic injection

Additional surgical procedure, including vitrectomy and cataract surgery. · people with endophthalmitis following intraocular surgery

Vitrectomy showed no clear difference in additional surgical procedure, including vitrectomy and cataract… compared with vitreous tap biopsy and antibiotic injection (low certainty).

1 finding from 1 review

Laparoscopic retroperitoneal adrenalectomy vs laparoscopic transperitoneal adrenalectomy

Early morbidity (any complication during the first 30 to 60 days following surgery)

It is very uncertain whether laparoscopic retroperitoneal adrenalectomy changes early morbidity (any complication during the first 30 to 60 days… compared with laparoscopic transperitoneal adrenalectomy (very low certainty).

1 finding from 1 review

Transmyocardial laser revascularization vs medical treatment

Early postoperative mortality Deaths in the 30 days after surgery · patients with refractory angina

Transmyocardial laser revascularization showed no clear difference in early postoperative mortality Deaths in the 30 days after surgery compared with medical treatment (high certainty).

1 finding from 1 review

Summary of findings table 1: comparison of operation types: early results of needle fasciotomy vs limited fasciectomy

DASH hand function score at 3 months Major outcome group 1 (hand function) (scores between 0 and 100, where 0 represents no impairment in hand function and 100 represents maximum impairment in hand function) · 125 hands in 121 participants with Dupuytren's disease of the fingers for early outcomes (van Rijssen 2006)
1 finding from 1 review

Bispectral index vs clinical signs

Occurrence of intraoperative awareness Time points of measure after surgery: 2 to 6 hours;12 hours; 1 day; 2 days; 3 days; 14 days; 30 days; or time point was not reported Measurement tools: simple questioning; interviews; or structured questionna... · adults undergoing surgery with general anaesthesia

Bispectral index may leads to lower occurrence of intraoperative awareness Time points of measure after… compared with clinical signs (low certainty).

1 finding from 1 review

Bispectral index vs ETAG

Occurrence of intraoperative awareness Time points of measure after surgery: 2 to 6 hours;12 hours; 1 day; 2 days; 3 days; 14 days; 30 days; or time point was not reported Measurement tools: simple questioning; interviews; or structured questionna... · adults undergoing surgery with general anaesthesia

BIS showed no clear difference in occurrence of intraoperative awareness Time points of measure after… compared with ETAG (low certainty).

1 finding from 1 review

Perioperative beta‐blockers vs placebo or usual care

Early all‐cause mortality (within 30 days) · adults undergoing non‐cardiac surgery under general anaesthesia (to include: low‐risk, medium‐risk, and high‐risk surgeries)

Perioperative beta‐blockers showed no clear difference in early all‐cause mortality (within 30 days) compared with placebo or standard care (low certainty).

1 finding from 1 review

Intervention not reported

Hospital length of stay (patients recovering from orthopaedic surgery) · patients recovering from surgery who otherwise would require acute hospital inpatient care

The intervention showed no clear difference in hospital length of stay (patients recovering from orthopaedic surgery) (moderate certainty).

1 finding from 1 review