Clinical failure · febrile neutropenia
It is very uncertain whether early discontinuation of antibiotic treatment changes clinical failure compared with treatment until neutropenia resolution (very low certainty).
1 finding from 1 review
Bacteraemia · febrile neutropenia
It is very uncertain whether early discontinuation of antibiotic treatment changes any bacteraemia compared with treatment until neutropenia resolution (very low certainty).
1 finding from 1 review
Risk of relapse (as defined by study authors) (HR) · participants with long‐term antidepressants for depressive disorders
Discontinuation with high‐intensity psychological interventions showed no clear difference in risk of relapse (as defined by study authors) (HR) compared with continuation (low certainty).
1 finding from 1 review
Withdrawal symptoms · participants with long‐term antidepressants for depressive disorders
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events · participants with long‐term antidepressants for depressive disorders
1 finding from 1 review
Depressive symptoms · participants with long‐term antidepressants for depressive disorders
1 finding from 1 review
Anxiety · participants with long‐term antidepressants for depressive disorders
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Quality of life · participants with long‐term antidepressants for depressive disorders
1 finding from 1 review
Social and occupational functioning · participants with long‐term antidepressants for depressive disorders
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Relapse · participants with long‐term antidepressants for depressive or anxiety disorders
1 finding from 1 review
Withdrawal symptoms · participants with long‐term antidepressants for depressive or anxiety disorders
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events · participants with long‐term antidepressants for depressive or anxiety disorders
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Depressive symptoms · participants with long‐term antidepressants for depressive or anxiety disorders
1 finding from 1 review
Anxiety · participants with long‐term antidepressants for depressive or anxiety disorders
1 finding from 1 review
Quality of life · participants with long‐term antidepressants for depressive or anxiety disorders
1 finding from 1 review
Social and occupational functioning · participants with long‐term antidepressants for depressive or anxiety disorders
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Lack of symptom control · people with mild to moderate esophagitis, symptomatic, aged > 18 years (mean age 73 years)
It is very uncertain whether abrupt discontinuation deprescribing changes lack of symptom control compared with continued use (very low certainty).
1 finding from 1 review
Adverse drug withdrawal events ‐ relapse (endoscopic findings) · people with mild to moderate esophagitis, symptomatic, aged > 18 years (mean age 73 years)
It is very uncertain whether abrupt discontinuation deprescribing changes adverse drug withdrawal events ‐ relapse (endoscopic findings) compared with continued use (very low certainty).
1 finding from 1 review
All‐cause mortality · Older adults, 50 years and older
Discontinuation by no treatment/placebo of antihypertensives showed no clear difference in all‐cause mortality compared with continuation (low certainty).
1 finding from 1 review
Fatal or nonfatal myocardial infarction · Older adults, 50 years and older
It is very uncertain whether discontinuation by no treatment/placebo of antihypertensives changes myocardial infarction (fatal and nonfatal) compared with continuation (very low certainty).
1 finding from 1 review