Question · asked by 1 review
Discontinuation by no treatment/placebo of antihypertensives vs continuation: All‐cause mortality
- Population
- Older adults, 50 years and older
- Intervention
- Discontinuation by no treatment/placebo of antihypertensives
- Comparison
- continuation
- Outcome
- All‐cause mortality
Discontinuation by no treatment/placebo of antihypertensives showed no clear difference in all‐cause mortality compared with continuation (low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Discontinuation by no treatment/placebo of antihypertensives vs continuation All‐cause mortality · Older adults, 50 years and older Discontinuation by no treatment/placebo of antihypertensives showed no clear difference in all‐cause mortality compared with continuation (low certainty). Withdrawal of antihypertensive drugs in older people (2020) · Cochrane Headline outcomes only | OR 2.08 [0.79, 5.46] | 4 studies · 630 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Withdrawal of antihypertensive drugs in older people 2020 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.