evidencegaps
Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

90 questions · 90 findings · 23 reviews · Cystic Fibrosis and Genetic Disorders

Sort:Best matchNewestHighest certaintyDownload CSV
No studies found 39 · 43.3%GRADE not reported 0 · 0%Very low 22 · 24.4%Low 22 · 24.4%Moderate 5 · 5.6%High 2 · 2.2%

L‐arginine vs placebo

Frequency of hospitalization (number of days in hospital) · sickle cell disease

It is very uncertain whether L‐arginine changes frequency of hospitalization (number of days in hospital) compared with placebo (very low certainty).

1 finding from 1 review

Single foetal haemoglobin inducer at any dose or duration vs another dose or dose regimen of the same foetal haemoglobin inducer

Transfusion‐free interval (days) · people with non‐transfusion‐dependent β‐thalassaemia

The review found no eligible studies for this question.

1 finding from 1 review

Two or more foetal haemoglobin inducers at any dose or duration vs a usual management protocol, placebo or a single foetal haemoglobin inducer

Transfusion‐free interval (days) · people with non‐transfusion‐dependent β‐thalassaemia

The review found no eligible studies for this question.

1 finding from 1 review

Short‐acting inhaled beta‐2 agonists vs placebo

Number of exacerbations(as reported by number of hospitalisations and number of courses and days on antibiotics) · adults and children with cystic fibrosis

It is very uncertain whether short‐acting inhaled beta‐2 agonists changes number of exacerbations(as reported by number of hospitalisations… compared with placebo (very low certainty).

1 finding from 1 review