Findings

What do systematic reviews say?

429 questions · 431 findings · 83 reviews

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No studies found 89 · 20.6%GRADE not reported 34 · 7.9%Very low 93 · 21.6%Low 110 · 25.5%Moderate 79 · 18.3%High 26 · 6%

Acupuncture as an addition to the routine primary care that trial participants were receiving from their physicians vs routine primary physician care alone

Outcomesa · patients with hip osteoarthritis

The review found no eligible studies for this question.

1 finding from 1 review

Acupuncture for hip osteoarthritis 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Acupuncture as an addition to the routine primary care that trial participants were receiving from their physicians vs routine primary physician care alone

Pain (short term) WOMAC scale from 0 to 20 points (higher is worse pain). · patients with hip osteoarthritis

1 finding from 1 review

Acupuncture for hip osteoarthritis 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 137 participants
Low

Acupuncture as an addition to the routine primary care that trial participants were receiving from their physicians vs routine primary physician care alone

Function (short‐term) WOMAC scale from: 0 to 100 (higher is worse function). · patients with hip osteoarthritis

1 finding from 1 review

Acupuncture for hip osteoarthritis 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 137 participants
Low

HAART + ABV vs HAART alone

All‐cause mortality · HIV‐infected adults with severe (T1) Kaposi's sarcoma

HAART + ABV showed no clear difference in mortality compared with HAART alone (moderate certainty).

1 finding from 1 review

Treatment of severe or progressive Kaposi's sarcoma in HIV‐infected adults 2014 · Cochrane Headline outcomes only
RR 0.92 [0.45, 1.88]
1 study · 100 participants
Moderate

HAART + ABV vs HAART alone

Progressive disease · HIV‐infected adults with severe (T1) Kaposi's sarcoma

HAART + ABV probably leads to lower progressive disease compared with HAART alone (moderate certainty).

1 finding from 1 review

Treatment of severe or progressive Kaposi's sarcoma in HIV‐infected adults 2014 · Cochrane Headline outcomes only
RR 0.1 [0.01, 0.75]
1 study · 100 participants
Moderate

HAART + ABV vs HAART alone

Clinical response ‐ complete response · HIV‐infected adults with severe (T1) Kaposi's sarcoma

HAART + ABV showed no clear difference in clinical response ‐ complete response compared with HAART alone (moderate certainty).

1 finding from 1 review

Treatment of severe or progressive Kaposi's sarcoma in HIV‐infected adults 2014 · Cochrane Headline outcomes only
RR 2 [0.64, 6.22]
1 study · 100 participants
Moderate

HAART + ABV vs HAART alone

Clinical response ‐ stable disease · HIV‐infected adults with severe (T1) Kaposi's sarcoma

HAART + ABV probably leads to lower clinical response ‐ stable disease compared with HAART alone (moderate certainty).

1 finding from 1 review

Treatment of severe or progressive Kaposi's sarcoma in HIV‐infected adults 2014 · Cochrane Headline outcomes only
RR 0.06 [0, 0.99]
1 study · 100 participants
Moderate

HAART + ABV vs HAART alone

Adverse events · HIV‐infected adults with severe (T1) Kaposi's sarcoma

HAART + ABV showed no clear difference in adverse events compared with HAART alone (moderate certainty).

1 finding from 1 review

Treatment of severe or progressive Kaposi's sarcoma in HIV‐infected adults 2014 · Cochrane Headline outcomes only
RR 0.88 [0.59, 1.32]
1 study · 100 participants
Moderate

Endovascular therapy plus conventional medical treatment vs medical treatment

Fatal/non‐fatal stroke in the territory of the treated vertebral artery stenosis(assessed after 30 days post‐randomisation to completion of · people with vertebral artery stenosis

Endovascular treat ment plus medical treatment showed no clear difference in fatal/non‐fatal stroke in the territory of the treated vertebral… compared with medical treatment alone (moderate certainty).

1 finding from 1 review

Percutaneous transluminal angioplasty and stenting for vertebral artery stenosis 2022 · Cochrane Headline outcomes only
RR 0.51 [0.26, 1.01]
3 studies · 349 participants
Moderate

Laxative plus bulking agent vs laxative alone

Incidence of postpartum constipation · postpartum women who underwent surgical repair of third degree perineal tears

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for preventing postpartum constipation 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Laxative plus bulking agent vs laxative alone

Adverse effects on women: faecal incontinence during first 10 postpartum days · postpartum women who underwent surgical repair of third degree perineal tears

It is very uncertain whether laxative plus bulking agent changes adverse effects on women: faecal incontinence during first 10… compared with laxative alone (very low certainty).

1 finding from 1 review

Interventions for preventing postpartum constipation 2020 · Cochrane Headline outcomes only
RR 1.81 [1.01, 3.23]
1 study · 147 participants
Very low

Does treatment guided by serial BNP or NT‐proBNP monitoring improve outcomes vs treatment guided by clinical assessment alone?

Heart failure mortality · patients with heart failure

Does treatment guided by serial BNP or NT‐proBNP monitoring improve… showed no clear difference in heart failure mortality compared with treatment guided by clinical assessment alone? (low certainty).

1 finding from 1 review

B‐type natriuretic peptide‐guided treatment for heart failure 2016 · Cochrane Headline outcomes only
RR 0.84 [0.54, 1.3]
6 studies · 853 participants
Low

Does treatment guided by serial BNP or NT‐proBNP monitoring improve outcomes vs treatment guided by clinical assessment alone?

Heart failure hospitalisation (RR) · patients with heart failure

Does treatment guided by serial BNP or NT‐proBNP monitoring improve… may leads to lower heart failure admissions compared with treatment guided by clinical assessment alone? (low certainty).

1 finding from 1 review

B‐type natriuretic peptide‐guided treatment for heart failure 2016 · Cochrane Headline outcomes only
RR 0.7 [0.61, 0.8]
10 studies · 1928 participants
Low

Shengmai plus usual treatment vs usual treatment alone

Lack of improvement in heart failure ( NYHA class improved < I class or worsening of heart failure) · patients with heart failure

Shengmai plus usual treatment may leads to lower lack of improvement in heart failure (NYHA class improved < I class… compared with usual treatment alone (low certainty).

1 finding from 1 review

Shengmai (a traditional Chinese herbal medicine) for heart failure 2014 · Cochrane Headline outcomes only
RR 0.37 [0.26, 0.51]
10 studies · 672 participants
Low

Shengmai plus usual treatment vs usual treatment alone

Mean change in quality of life Minnesota Living with Heart Failure Questionnaire (MLWHF) score · patients with heart failure

1 finding from 1 review

Shengmai (a traditional Chinese herbal medicine) for heart failure 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
Low

IV or oral iron alone vs no treatment

Red blood cell transfusions (Subnet based on 69 studies including 18,684 participants) · patients at any age with solid cancer or haematological malignancy

IV or oral iron alone showed no clear difference in red blood cell transfusions (Subnet based on 69 studies including… compared with no treatment (low certainty).

1 finding from 1 review

Intravenous iron versus oral iron versus no iron with or without erythropoiesis‐ stimulating agents (ESA) for cancer… 2022 · Cochrane Headline outcomes only
RR 0.74 [0.43, 1.28]
Studies not reported
Low

IV or oral iron alone vs no treatment

Overall mortality4 (Subnet based on 71 studies including 21,576 participants) · patients at any age with solid cancer or haematological malignancy

IV or oral iron alone showed no clear difference in overall mortality4 (Subnet based on 71 studies including 21,576… compared with no treatment (low certainty).

1 finding from 1 review

Intravenous iron versus oral iron versus no iron with or without erythropoiesis‐ stimulating agents (ESA) for cancer… 2022 · Cochrane Headline outcomes only
RR 1.5 [0.63, 3.56]
Studies not reported
Low

IV or oral iron alone vs no treatment

Thromboembolic events · patients at any age with solid cancer or haematological malignancy

The review found no eligible studies for this question.

1 finding from 1 review

Intravenous iron versus oral iron versus no iron with or without erythropoiesis‐ stimulating agents (ESA) for cancer… 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

IV or oral iron alone vs no treatment

Thrombocytopenia or haemorrhage5 (Subnet based on 13 studies including 2744 participants) · patients at any age with solid cancer or haematological malignancy

The review found no eligible studies for this question.

1 finding from 1 review

Intravenous iron versus oral iron versus no iron with or without erythropoiesis‐ stimulating agents (ESA) for cancer… 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

IV or oral iron alone vs no treatment

Hypertension5 (Subnet based on 24 studies including 8383 participants) · patients at any age with solid cancer or haematological malignancy

The review found no eligible studies for this question.

1 finding from 1 review

Intravenous iron versus oral iron versus no iron with or without erythropoiesis‐ stimulating agents (ESA) for cancer… 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found