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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

2,653 questions in 194 reviews · Gynaecology and Fertility

current versions
No studies 531 · 20%Ungraded 76 · 2.9%Very low 826 · 31.1%Low 855 · 32.2%Moderate 341 · 12.9%High 24 · 0.9%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Warmed, or warmed and humidified CO2 vs unwarmed and unhumidified CO2
Adverse events · women undergoing gynaecological laparoscopic procedures
Interventions to reduce shoulder pain following gynaecological laparoscopic procedures (2019) · Cochrane
no estimate extractedNRNo studies
Warmed, or warmed and humidified CO2 vs unwarmed and unhumidified CO2
Analgesia usage (morphine mg) over 48 hours post‐operatively · women undergoing gynaecological laparoscopic procedures
Interventions to reduce shoulder pain following gynaecological laparoscopic procedures (2019) · Cochrane
no estimate extracted1 study · 95 participantsLow
Gasless laparoscopy vs CO2 insufflation
Incidence of STP · women undergoing gynaecological laparoscopic procedures
Interventions to reduce shoulder pain following gynaecological laparoscopic procedures (2019) · Cochrane
no estimate extractedNRNo studies
Gasless laparoscopy vs CO2 insufflation
Severity of STP over 72 hours post‐operatively · women undergoing gynaecological laparoscopic procedures
Interventions to reduce shoulder pain following gynaecological laparoscopic procedures (2019) · Cochrane
no estimate extracted1 study · 54 participantsLow
Gasless laparoscopy vs CO2 insufflation
Adverse events · women undergoing gynaecological laparoscopic procedures
Interventions to reduce shoulder pain following gynaecological laparoscopic procedures (2019) · Cochrane
OR 2.56 [0.25, 26.28]1 study · 54 participantsLow
Gasless laparoscopy vs CO2 insufflation
Analgesia usage · women undergoing gynaecological laparoscopic procedures
Interventions to reduce shoulder pain following gynaecological laparoscopic procedures (2019) · Cochrane
no estimate extractedNRNo studies
Specific technique vs standard technique
Adverse events · women undergoing a diagnostic or operative laparoscopic gynaecological procedure
Interventions to reduce shoulder pain following gynaecological laparoscopic procedures (2019) · Cochrane
no estimate extracted1 study · 74 participantsUngraded
Specific technique vs standard technique
Analgesia usage during study · women undergoing a diagnostic or operative laparoscopic gynaecological procedure
Interventions to reduce shoulder pain following gynaecological laparoscopic procedures (2019) · Cochrane
no estimate extracted4 studies · 570 participantsLow
Fluid instillation vs no fluid instillation
Incidence of STP at 24 hours post‐operatively · women undergoing a diagnostic or operative laparoscopic gynaecological procedure
Interventions to reduce shoulder pain following gynaecological laparoscopic procedures (2019) · Cochrane
OR 0.38 [0.22, 0.66]2 studies · 220 participantsModerate
Fluid instillation vs no fluid instillation
Severity of STP at 24 hours post‐operatively · women undergoing a diagnostic or operative laparoscopic gynaecological procedure
Interventions to reduce shoulder pain following gynaecological laparoscopic procedures (2019) · Cochrane
no estimate extracted2 studies · 205 participantsModerate
Fluid instillation vs no fluid instillation
Adverse events · women undergoing a diagnostic or operative laparoscopic gynaecological procedure
Interventions to reduce shoulder pain following gynaecological laparoscopic procedures (2019) · Cochrane
no estimate extractedNRNo studies
Fluid instillation vs no fluid instillation
Analgesia usage (meperidine mg) within 24 hours post‐operatively · women undergoing a diagnostic or operative laparoscopic gynaecological procedure
Interventions to reduce shoulder pain following gynaecological laparoscopic procedures (2019) · Cochrane
no estimate extracted2 studies · 205 participantsLow
Intraperitoneal drain vs no intraperitoneal drain
Incidence of STP at 24 hours post‐operatively · women undergoing a diagnostic or operative laparoscopic gynaecological procedure
Interventions to reduce shoulder pain following gynaecological laparoscopic procedures (2019) · Cochrane
OR 0.3 [0.2, 0.46]3 studies · 417 participantsLow
TLS with conventional morphological assessment of still TLS images vs conventional incubation and assessment
Live birth or ongoing pregnancy · couples undergoing assisted reproductive technology
Time‐lapse systems for embryo incubation and assessment in assisted reproduction (2019) · Cochrane
OR 0.91 [0.67, 1.23]3 studies · 826 participantsLow
TLS utilising embryo selection software vs conventional incubation and assessment
Miscarriage · couples undergoing ART
Time‐lapse systems for embryo incubation and assessment in assisted reproduction (2019) · Cochrane
OR 0.63 [0.45, 0.89]3 studies · 1617 participantsVery low
TLS utilising embryo selection software vs conventional incubation and assessment
Stillbirth · couples undergoing ART
Time‐lapse systems for embryo incubation and assessment in assisted reproduction (2019) · Cochrane
no estimate extracted1 study · 600 participantsUngraded
TLS utilising embryo selection software vs conventional incubation and assessment
Clinical pregnancy · couples undergoing ART
Time‐lapse systems for embryo incubation and assessment in assisted reproduction (2019) · Cochrane
OR 0.95 [0.78, 1.16]3 studies · 1617 participantsVery low
TLS with conventional morphological assessment of still TLS images vs conventional incubation and assessment
Miscarriage · couples undergoing assisted reproductive technology
Time‐lapse systems for embryo incubation and assessment in assisted reproduction (2019) · Cochrane
OR 1.9 [0.99, 3.61]3 studies · 826 participantsLow
TLS with conventional morphological assessment of still TLS images vs conventional incubation and assessment
Stillbirth · couples undergoing assisted reproductive technology
Time‐lapse systems for embryo incubation and assessment in assisted reproduction (2019) · Cochrane
OR 1 [0.13, 7.49]1 study · 76 participantsLow
TLS with conventional morphological assessment of still TLS images vs conventional incubation and assessment
Clinical pregnancy · couples undergoing assisted reproductive technology
Time‐lapse systems for embryo incubation and assessment in assisted reproduction (2019) · Cochrane
OR 1.06 [0.79, 1.41]4 studies · 875 participantsLow
TLS utilising embryo selection software vs TLS with conventional morphological assessment of still TLS images
Live birth or ongoing pregnancy · couples undergoing assisted reproductive technology
Time‐lapse systems for embryo incubation and assessment in assisted reproduction (2019) · Cochrane
OR 0.61 [0.32, 1.2]1 study · 163 participantsVery low
TLS utilising embryo selection software vs TLS with conventional morphological assessment of still TLS images
Miscarriage · couples undergoing assisted reproductive technology
Time‐lapse systems for embryo incubation and assessment in assisted reproduction (2019) · Cochrane
OR 1.39 [0.64, 3.01]2 studies · 463 participantsVery low
TLS utilising embryo selection software vs TLS with conventional morphological assessment of still TLS images
Stillbirth · couples undergoing assisted reproductive technology
Time‐lapse systems for embryo incubation and assessment in assisted reproduction (2019) · Cochrane
no estimate extractedNRNo studies
TLS utilising embryo selection software vs TLS with conventional morphological assessment of still TLS images
Clinical pregnancy · couples undergoing assisted reproductive technology
Time‐lapse systems for embryo incubation and assessment in assisted reproduction (2019) · Cochrane
OR 0.97 [0.67, 1.42]2 studies · 463 participantsVery low
TLS utilising embryo selection software vs conventional incubation and assessment
Live birth or ongoing pregnancy · couples undergoing ART
Time‐lapse systems for embryo incubation and assessment in assisted reproduction (2019) · Cochrane
OR 1.12 [0.92, 1.36]3 studies · 1617 participantsVery low
37°C vs any lower temperature
Live birth · subfertile women undergoing IVF or IVF/ICSI
Temperature of embryo culture for assisted reproduction (2019) · Cochrane
no estimate extracted1 study · 1 participantsUngraded
37°C vs any lower temperature
Miscarriage · subfertile women undergoing IVF or IVF/ICSI
Temperature of embryo culture for assisted reproduction (2019) · Cochrane
OR 0.9 [0.52, 1.55]1 study · 412 participantsVery low
37°C vs any lower temperature
Clinical pregnancy · subfertile women undergoing IVF or IVF/ICSI
Temperature of embryo culture for assisted reproduction (2019) · Cochrane
OR 1.08 [0.73, 1.6]1 study · 412 participantsVery low
37°C vs any lower temperature
Ongoing pregnancy · subfertile women undergoing IVF or IVF/ICSI
Temperature of embryo culture for assisted reproduction (2019) · Cochrane
OR 1.1 [0.75, 1.62]1 study · 412 participantsVery low
37°C vs any lower temperature
Multiple pregnancy · subfertile women undergoing IVF or IVF/ICSI
Temperature of embryo culture for assisted reproduction (2019) · Cochrane
OR 0.8 [0.31, 2.07]1 study · 412 participantsVery low
37°C vs any lower temperature
Adverse events ‐ not reported · subfertile women undergoing IVF or IVF/ICSI
Temperature of embryo culture for assisted reproduction (2019) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Comparator · couples with unexplained infertility
Interventions for unexplained infertility: a systematic review and network meta‐analysis (2019) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Comparator · couples with unexplained infertility
Interventions for unexplained infertility: a systematic review and network meta‐analysis (2019) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Expectant management · couples with unexplained infertility
Interventions for unexplained infertility: a systematic review and network meta‐analysis (2019) · Cochrane
OR 1.64 [0.99, 2.73]NRVery low
Intervention NR
OS · couples with unexplained infertility
Interventions for unexplained infertility: a systematic review and network meta‐analysis (2019) · Cochrane
OR 0.73 [0.38, 1.42]NRVery low
Intervention NR
IUI · couples with unexplained infertility
Interventions for unexplained infertility: a systematic review and network meta‐analysis (2019) · Cochrane
OR 1.94 [1.05, 3.57]NRVery low
Intervention NR
OS‐IUI · couples with unexplained infertility
Interventions for unexplained infertility: a systematic review and network meta‐analysis (2019) · Cochrane
OR 1.3 [0.68, 2.5]NRLow
Intervention NR
Moderate/severe OHSS · couples with unexplained infertility
Interventions for unexplained infertility: a systematic review and network meta‐analysis (2019) · Cochrane
OR 2.5 [0.92, 6.76]5 studies · 958 participantsModerate
Intervention NR
Expectant management · couples with unexplained infertility
Interventions for unexplained infertility: a systematic review and network meta‐analysis (2019) · Cochrane
OR 1.01 [0.51, 1.98]NRLow
Intervention NR
OS · couples with unexplained infertility
Interventions for unexplained infertility: a systematic review and network meta‐analysis (2019) · Cochrane
OR 1.2 [0.57, 2.52]NRLow
Intervention NR
IUI · couples with unexplained infertility
Interventions for unexplained infertility: a systematic review and network meta‐analysis (2019) · Cochrane
OR 1.33 [0.67, 3.58]NRLow
Intervention NR
OS‐IUI · couples with unexplained infertility
Interventions for unexplained infertility: a systematic review and network meta‐analysis (2019) · Cochrane
OR 1.17 [0.64, 2.12]NRLow
Intervention NR
Comparator · couples with unexplained infertility
Interventions for unexplained infertility: a systematic review and network meta‐analysis (2019) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Expectant management/IUI · couples with unexplained infertility
Interventions for unexplained infertility: a systematic review and network meta‐analysis (2019) · Cochrane
OR 3.07 [1, 9.41]NRLow
Intervention NR
OS · couples with unexplained infertility
Interventions for unexplained infertility: a systematic review and network meta‐analysis (2019) · Cochrane
OR 1.09 [0.38, 3.15]NRVery low
Intervention NR
OS‐IUI · couples with unexplained infertility
Interventions for unexplained infertility: a systematic review and network meta‐analysis (2019) · Cochrane
OR 0.8 [0.37, 1.73]NRLow
Screening hysteroscopy vs no hysteroscopy
Live birth · women with unexplained subfertility wishing to conceive spontaneously
Screening hysteroscopy in subfertile women and women undergoing assisted reproduction (2019) · Cochrane
RR 4.3 [2.29, 8.07]1 study · 200 participantsVery low
Screening hysteroscopy vs no hysteroscopy
Adverse events · women with unexplained subfertility wishing to conceive spontaneously
Screening hysteroscopy in subfertile women and women undergoing assisted reproduction (2019) · Cochrane
no estimate extracted1 study · 1 participantsVery low
Screening hysteroscopy vs no hysteroscopy
Clinical pregnancy · women with unexplained subfertility wishing to conceive spontaneously
Screening hysteroscopy in subfertile women and women undergoing assisted reproduction (2019) · Cochrane
RR 3.8 [2.31, 6.24]1 study · 200 participantsVery low
Screening hysteroscopy vs no hysteroscopy
Miscarriage · women with unexplained subfertility wishing to conceive spontaneously
Screening hysteroscopy in subfertile women and women undergoing assisted reproduction (2019) · Cochrane
RR 2.8 [1.05, 7.48]1 study · 200 participantsVery low