Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them
It is very uncertain whether chlorhexidine (CHX) changes reduction in level of contamination by particles >5 um (droplets) at… compared with ozonated water (very low certainty).
1 finding from 1 review
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
P-hydroxybenzoic acid showed no clear difference in presence of dry socket compared with placebo; GRADE not reported.
1 finding from 1 review
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · People aged 12 years and over with painful TMD lasting 3 months or longer
Hope-based intervention showed no clear difference in pain intensity compared with pain education; GRADE not reported.
1 finding from 1 review
Swelling or flare-up · People aged 10 years or above requiring root canal treatment; permanent teeth with completely formed apex and without internal resorption
It is very uncertain whether single-visit root canal treatment changes swelling or flare-up compared with multiple-visit root canal treatment (two or more visits) (very low certainty).
1 finding from 1 review
Mean caries increment (mean number of new cavitated occlusal lesions) · Children with caries-free or non-cavitated carious lesion primary molars, aged 3-7 years (paediatric department, dental hospital, France)
1 finding from 1 review
All CVD-related death · Patients with cardiovascular disease and chronic periodontitis
The review found no eligible studies for this question.
1 finding from 1 review
Incidence of NHAP · Residents of nursing homes and other long-term care facilities
1 finding from 1 review
Incidence of NHAP, follow-up 8-30 months, 5018 (5 studies), Low. Not pooled (individual and cluster-randomised designs, varying effect measures and follow-up). Component estimates: Bourigault HR 0.65 (0.29 to 1.46;…
5 studies · 5018 participants
Low
Healing of MRONJ (soft tissue healing) · Women with osteoporosis and established MRONJ
It is very uncertain whether concentrated growth factor (CGF) and primary wound closure changes healing of MRONJ (soft tissue healing) compared with primary wound closure only (very low certainty).
1 finding from 1 review
Mortality (all‐cause) · Residents of nursing homes and other long-term care facilities
1 finding from 1 review
All-cause mortality, follow-up 12-30 months, 3764 (3 studies), Very low. Not pooled. Adachi RR 0.80 (0.40 to 1.58; 88); Juthani-Mehta HR 1.16 (0.88 to 1.53; 834); Zimmerman adjusted IRR 0.83 (0.61 to 1.12; 1606).…
3 studies · 3764 participants
Very low
Healing of MRONJ · People with established (manifest) MRONJ
It is very uncertain whether platelet-rich fibrin after bone surgery changes healing of MRONJ (mucosal integrity and absence of infection) compared with bone surgery alone (very low certainty).
1 finding from 1 review
Adverse events · People aged 12 years and over with painful TMD lasting 3 months or longer
1 finding from 1 review
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Heal-all tissue patch showed no clear difference in presence of dry socket compared with no treatment; GRADE not reported.
1 finding from 1 review
Dental attendance · School children (aged 4 to 15 years), primary and secondary schools in the UK and India
1 finding from 1 review
Data not pooled; 6281 participants (4 RCTs); Very low. There was substantial heterogeneity, in part due to study design (3 cluster-RCTs and 1 individually randomised trial). We are unable to draw conclusions about this…
4 studies · 6281 participants
Very low
Cardiovascular events · Patients with cardiovascular disease and chronic periodontitis
1 finding from 1 review
All cardiovascular events (Follow-up: 6 to 25 months): One study of 303 participants assessed this outcome; however, we considered data were unreliable as participants were followed up for different lengths of time,…
1 study · 303 participants
Very low
Tooth loss · Adults with a clinical diagnosis of (chronic) periodontitis (1999 classification); studies of aggressive periodontitis, systemic disorders…
The review found no eligible studies for this question.
1 finding from 1 review
Dental attendance · School children, primary and secondary schools in India
It is very uncertain whether traditional screening with motivation (oral health education and… changes dental attendance compared with traditional screening alone (very low certainty).
1 finding from 1 review
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Chlorhexidine rinse (0.12% and 0.2%, pre- and post-extraction) probably leads to lower presence of dry socket compared with placebo or no treatment (moderate certainty).
1 finding from 1 review
Quality of life indicators · People with diabetes mellitus (type 1 or type 2, mostly type 2) and periodontitis, at least 16 years of age
1 finding from 1 review
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Gaseous ozone showed no clear difference in presence of dry socket compared with placebo or control; GRADE not reported.
1 finding from 1 review
Retention of sealant (complete or partial retention) · Children with caries-free second primary molars, aged 4-8 years (dental clinic, Turkey and Spain)
1 finding from 1 review
Effect estimate not calculable; 69 (2 studies). Retention equivocal: Unal 2015 100% (fluoride resin) vs 96.0% (resin) at 12 months; Baca 2007 84.1% (fluoride resin) vs 97.7% (resin) at 12 months; at 24 months 87.8% vs…
2 studies · 69 participants
Very low