Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

573 questions · 674 findings · 44 reviews · Oral Health

No studies found 253 · 37.5%GRADE not reported 258 · 38.3%Very low 106 · 15.7%Low 38 · 5.6%Moderate 15 · 2.2%High 4 · 0.6%

Autologous platelet concentrate (PRP/PRF) in socket vs No blood product (conventional)

Presence of dry socket · Adults with mandibular third molars requiring removal

Autologous platelet concentrate (PRP/PRF) in socket may leads to lower alveolar osteitis compared with no blood product (conventional) (low certainty).

1 finding from 1 review

Tetracycline + SRP vs SRP

Percentage of bleeding on probing (BOP) · Adults with aggressive periodontitis

The review found no eligible studies for this question.

2 findings from 1 review

Primary (complete) wound closure vs Secondary (partial) wound closure

Maximal mouth opening (interincisal distance) · Adults with mandibular third molars requiring removal

Primary (complete) wound closure showed no clear difference in maximum mouth opening (mean) compared with secondary (partial) wound closure; GRADE not reported.

1 finding from 1 review

Mechanical (high-volume) irrigation vs Manual (low-volume) irrigation

Presence of dry socket · Adults with mandibular third molars requiring removal

It is very uncertain whether mechanical (high-volume) irrigation changes alveolar osteitis compared with manual (low-volume) irrigation (very low certainty).

1 finding from 1 review

Piezoelectric bone removal vs Conventional rotary handpiece

Trismus / maximum mouth opening (mean) · Adults with mandibular third molars requiring removal

Piezoelectric bone removal led to higher trismus / maximum mouth opening (mean) compared with conventional rotary handpiece; GRADE not reported.

1 finding from 1 review

Autologous platelet concentrate (PRP/PRF) in socket vs No blood product (conventional)

Postoperative pain (mean) · Adults with mandibular third molars requiring removal

Autologous platelet concentrate (PRP/PRF) in socket showed no clear difference in postoperative pain (mean) compared with no blood product (conventional); GRADE not reported.

1 finding from 1 review