Severe intraventricular haemorrhage · neonates with sepsis
It is very uncertain whether pentoxifylline with antibiotics (any dose or duration) changes severe intraventricular haemorrhage compared with placebo or no intervention (very low certainty).
1 finding from 1 review
Periventricular leukomalacia · neonates with sepsis
It is very uncertain whether pentoxifylline with antibiotics (any dose or duration) changes periventricular leukomalacia compared with placebo or no intervention (very low certainty).
1 finding from 1 review
Length of hospital stay · neonates with sepsis
Pentoxifylline with antibiotics (any dose or duration) showed no clear difference in length of hospital stay (LOS) in days compared with placebo or no intervention (low certainty).
1 finding from 1 review
Necrotising enterocolitis · neonates with sepsis
It is very uncertain whether pentoxifylline with antibiotics (any dose or duration) changes necrotising enterocolitis, any Bell stage compared with placebo or no intervention (very low certainty).
1 finding from 1 review
Retinopathy of prematurity · neonates with sepsis
It is very uncertain whether pentoxifylline with antibiotics (any dose or duration) changes retinopathy of prematurity, any stage compared with placebo or no intervention (very low certainty).
1 finding from 1 review
Serious neonatal morbidity
It is very uncertain whether cervical cerclage in combination with antibiotics and tocolytics changes serious neonatal morbidity (Reported in Miller 2014 as 'composite… compared with cervical cerclage alone (very low certainty).
1 finding from 1 review
Perinatal loss: all ‐ including miscarriages and stillbirth (Note: data not available for neonatal death)
It is very uncertain whether cervical cerclage in combination with antibiotics and tocolytics changes perinatal loss: all ‐ including miscarriages and stillbirth (Note:… compared with cervical cerclage alone (very low certainty).
1 finding from 1 review
Baby discharged home healthy
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Death of the baby before discharge: neonatal death
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Stillbirth (death after 24 weeks inutero)
1 finding from 1 review
Preterm birth less than 34 weeks' gestation
It is very uncertain whether cervical cerclage in combination with antibiotics and tocolytics changes preterm birth < 34 completed weeks of pregnancy compared with cervical cerclage alone (very low certainty).
1 finding from 1 review
Time to first exacerbation requiring intravenous antibiotics · adults and children with cystic fibrosis
1 finding from 1 review
Adverse effects of antibiotics · adults and children with cystic fibrosis and a positive microbiological isolate of P aeruginosa from a respiratory tract specimen
1 finding from 1 review
Adverse effects of antibiotics: proportion of participants with one or more serious adverse event · adults and children with cystic fibrosis and a positive microbiological isolate of P aeruginosa from a respiratory tract specimen
Cycled inhaled tobramycin (TNS) probably leads to lower adverse effects of antibiotics: proportion of participants with one… compared with culture‐based TNS (moderate certainty).
1 finding from 1 review
Adverse effects of antibiotics: proportion of participants with one or more serious adverse event · adults and children with cystic fibrosis and a positive microbiological isolate of P aeruginosa from a respiratory tract specimen
Ciprofloxacin showed no clear difference in adverse effects of antibiotics: proportion of participants with one… compared with placebo added to cycled and culture‐based inhaled tobramycin (TNS)… (moderate certainty).
1 finding from 1 review
Adverse effects of antibiotics: severe cough · adults and children with cystic fibrosis and a positive microbiological isolate of P aeruginosa from a respiratory tract specimen
It is very uncertain whether oral ciprofloxacin and inhaled colistin changes adverse effects of antibiotics: severe cough compared with inhaled tobramycin (TNS) (very low certainty).
1 finding from 1 review
Adverse effects of antibiotics: leading to trial discontinuation · adults and children with cystic fibrosis and a positive microbiological isolate of P aeruginosa from a respiratory tract specimen
1 finding from 1 review
Number experiencing adverse effects · children with cystic fibrosis and a new culture positive for P aeruginosa
Inhaled tobramycin (TNS) plus oral azithromycin showed no clear difference in adverse effects of antibiotics: number of participants experiencing… compared with TNS plus oral placebo (moderate certainty).
1 finding from 1 review
Adverse effects of antibiotics · adults and children with cystic fibrosis and a positive microbiological isolate of P aeruginosa from a respiratory tract specimen
1 finding from 1 review
Adverse effects of antibiotics: number of participants reporting a serious adverse event · children and adolescents with cystic fibrosis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found