Findings

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Evidence found and GRADE certainty

4,534 questions · 5,247 findings · 456 reviews

No studies found 1,142 · 21.8%GRADE not reported 1,503 · 28.6%Very low 1,040 · 19.8%Low 869 · 16.6%Moderate 554 · 10.6%High 139 · 2.6%

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Vitamin D vs placebo or no intervention

Adverse effect: hypercalciuria As defined by trialists Time frame: 3 months · children under 5 years of age

Vitamin D showed no clear difference in adverse effect: hypercalciuria As defined by trialistsTime frame:… compared with placebo or no intervention (moderate certainty).

1 finding from 1 review

Vitamin D vs placebo or no intervention

Hypercalcaemia · children under 5 years of age

It is very uncertain whether vitamin D changes adverse effect: hypercalcaemia As defined by trialistsTime frame:… compared with placebo or no intervention (very low certainty).

1 finding from 1 review

SOCIAL SKILLS vs no intervention

Teacher‐rated social skills Measured by: Conners Behavior Rating Scale: Social Problems Index; Strength and Difficulties Questionnaire: Prosocial Behaviour Subscale (teacher‐rated); Social Skills Improvement System; Social Skills Rating Scale: Coo... · Children and adolescents with ADHD
1 finding from 1 review

SOCIAL SKILLS vs no intervention

Parent‐rated social skills Measured by: Social Skills Rating Scale; Weiss Functional Impairment Scale: Social Acitivities Domain (parent‐rated); Strength and Difficulties Questionnaire: Prosocial Behavior Subscale; Social Skills Improvement System · Children and adolescents with ADHD
1 finding from 1 review

SOCIAL SKILLS vs no intervention

Teacher‐rated general behaviour Measured by: Self‐Control Rating Scale; Conners Behavior Rating Scale: Aggressiveness Index; Disruptive Behavior Disorders Rating Scale; Conners Teacher Rating Scale: Conduct Problems Index; Strengths and Difficulti... · Children and adolescents with ADHD
1 finding from 1 review

SOCIAL SKILLS vs no intervention

Parent‐rated general behaviour Measured by: Strengths and Difficulties Questionnaire (parent‐rated; total scores); Conners Behavior Rating Scale: Aggressiveness Index; Disruptive Behavior Disorders Rating Scale; Behavior Rating Inventory of Execut... · Children and adolescents with ADHD
1 finding from 1 review

SOCIAL SKILLS vs no intervention

ADHD symptoms · Children and adolescents with ADHD
2 findings from 1 review

Standard ready‐to‐use therapeutic food (RUTF) provided at a dose that meets total daily nutritional requirements vs an alternative dietary approach

Recovery during intervention defined as achieving WHZ ≥ −2 and absence of oedema in 1 study; reaching a WHZ score > −2 and without oedema in 1 study; WHZ > −2 in 1 study; having a WHZ score ≥ 0 in 1 study; reaching 100% weight for height in 1 stud... · children aged 6 months‐5 years with SAM (and mixed HIV comorbidity), some of whom had been stabilised as inpatients pre‐trial

Standard ready‐to‐use therapeutic food (RUTF) provided at a dose… probably leads to higher recovery during intervention defined as achieving WHZ ≥ −2 and… compared with an alternative dietary approach (moderate certainty).

1 finding from 1 review

Standard ready‐to‐use therapeutic food (RUTF) provided at a dose that meets total daily nutritional requirements vs RUTF using an alternative formulation

Relapse during intervention defined as admission to inpatient therapeutic care, remain wasted, and dropouts during intervention period · children aged 6 months‐5 years with SAM (and mixed HIV comorbidity), some of whom had been stabilised as inpatients pre‐trial

Standard ready‐to‐use therapeutic food (RUTF) leads to lower relapse during intervention defined as admission to inpatient… compared with RUTF using an alternative formulation (high certainty).

1 finding from 1 review

Standard ready‐to‐use therapeutic food (RUTF) provided at a dose that meets total daily nutritional requirements vs RUTF using an alternative formulation

Mortality during intervention · children aged 6 months‐5 years with SAM (and mixed HIV comorbidity), some of whom had been stabilised as inpatients pre‐trial

Standard ready‐to‐use therapeutic food (RUTF) showed no clear difference in mortality during intervention compared with RUTF using an alternative formulation (moderate certainty).

1 finding from 1 review

Standard ready‐to‐use therapeutic food (RUTF) provided at a dose that meets total daily nutritional requirements vs RUTF using an alternative formulation

Rate of weight gain (g/kg/day) · children aged 6 months‐5 years with SAM (and mixed HIV comorbidity), some of whom had been stabilised as inpatients pre‐trial
1 finding from 1 review

Standard ready‐to‐use therapeutic food (RUTF) provided at a dose that meets total daily nutritional requirements vs an alternative dietary approach

Relapse during intervention defined as admission to inpatient therapeutic care or recurrence of oedema or systematic infections during the study period, and dropouts during intervention period · children aged 6 months‐5 years with SAM (and mixed HIV comorbidity), some of whom had been stabilised as inpatients pre‐trial

It is very uncertain whether standard ready‐to‐use therapeutic food (RUTF) provided at a dose… changes relapse during intervention defined as admission to inpatient… compared with an alternative dietary approach (very low certainty).

1 finding from 1 review

Standard ready‐to‐use therapeutic food (RUTF) provided at a dose that meets total daily nutritional requirements vs an alternative dietary approach

Mortality during intervention · children aged 6 months‐5 years with SAM (and mixed HIV comorbidity), some of whom had been stabilised as inpatients pre‐trial

It is very uncertain whether standard ready‐to‐use therapeutic food (RUTF) provided at a dose… changes mortality during intervention compared with an alternative dietary approach (very low certainty).

1 finding from 1 review