Summary of findings: lamotrigine probably leads to lower fatigue compared with placebo (moderate certainty).
Summary of findings: lamotrigine probably leads to higher nausea compared with placebo (moderate certainty).
Summary of findings: lamotrigine probably leads to higher diplopia compared with placebo (moderate certainty).
The review found no eligible studies for this question.
It is very uncertain whether summary of findings 2: PLD alone changes overall severe adverse events (grade > 3) compared with other conventional chemotherapy (very low certainty).
It is very uncertain whether summary of findings 2: PLD alone changes anaemia (grade ≥ 3) compared with other conventional chemotherapy (very low certainty).
It is very uncertain whether summary of findings 2: PLD alone changes hand‐foot syndrome (grade ≥ 3) compared with other conventional chemotherapy (very low certainty).
It is very uncertain whether summary of findings 2: PLD alone changes neurological (grade ≥ 3) compared with other conventional chemotherapy (very low certainty).
Summary of findings 2: PLD alone showed no clear difference in overall survival (OS) compared with other conventional chemotherapy (moderate certainty).
It is very uncertain whether summary of findings 2: PLD alone changes progression‐free survival (PFS) compared with other conventional chemotherapy (very low certainty).
Summary of findings table ‐ PUFA may leads to higher ADHD symptoms – improvement – medium term compared with placebo (low certainty).
Summary of findings table ‐ PUFA showed no clear difference in side effects – overall compared with placebo (moderate certainty).
Summary of findings table ‐ PUFA showed no clear difference in loss to compared with placebo (moderate certainty).
Summary of findings for exercise probably leads to lower rate of Falls (falls per person‐year) compared with control (moderate certainty).
Summary of findings for exercise showed no clear difference in number of people who experienced one or more falls compared with control (moderate certainty).
It is very uncertain whether summary of findings for exercise changes number of people sustaining one or more fall‐related fractures compared with control (very low certainty).